You may think:
"What doesn't kill you makes you stronger", right?
And: "If the health effects would be so bad, surely everyone would complain or do something?"
Not so fast...
In fact, air pollution's effects are so bad that millions of people die because of being exposed.
You may assume... "millions of people die every century"
"or ever decade?"
Yes, that's right.
Every single year...
But even in the developed world the effects are frightening.
More bad news?
These circumstances are not about to change. Air pollution levels are projected to only half in 2030 (if you're lucky).
So what's the solution?
This guide is thus not targeted towards governments or health institutions.
No, this guide is written for you.
You see, only you can save yourself.
Only you can change your life and dramatically reduce your air pollution exposure levels.
Stay with me to find out...
The grand strategy of beating air pollution: understanding your opponent
and making one calculated move at a time.
Even though you're reading a 25,000 words+ blog post, you don't have to read the entire blog post to get massive benefits.
Instead, find an interesting topic in the table of contents below and start reading. More reading and more taking action, of course, is better for getting more results.
I'll first tell you why so many people in society - even health conscious people - often completely ignore the health effects air pollutants.
Let me explain with an example:
Do you know someone taking supplements and trying to increase their sleep quality or improve their health? What is the statistical chance that person is also watching their air pollution exposure?
That chance is low.
Several reasons exist, but I think the most important reason is complacency. Most people also assume that the government knows best how to deal with the air pollution problem, and there's little they can personally do to change things.
That attitude can be hazardous to your health.
The entire economic system is based upon burning of fossil fuels that create air pollutants. Sure, if there's a cheap way in which the levels of a pollutant can be dramatically reduced, by a filter for example, then governments will support that change.
But stopping all air pollution?
If you'd stop the burning of all fossil fuels, the world economy would not just come to a halt--it would collapse.
The entire economic system of this planet is thus (indirectly) premised upon air pollution - fossil fuels need to be burned to burned to support that system.
Of course, not all air pollution originates from burning fossil fuels.
The situation is more complex:
(Just to showcase that air pollution does indeed have health effects...)
That's VOCs, mold, nitrogen dioxide...
Few people are really acquainted with these substances.
In my full blog post, I'll consider many other compounds as well, such as sulfur dioxide, pollen and germs, asbestos, carbon monoxide, and more. Keep in mind that you don't need to remember all these, you just need to be aware of what's "out there" every day.
Let me tell you why...
I'll give you a simple analogy why air pollution is so dangerous:
In fact, you may even think you need to eat more food to compensate for your illness.
Air pollution is like that - it flies deceptively under the radar. Every day, air pollution does a small amount of damage to your health.
Exposure to pollutant is not like breaking your leg...
Or a car crash...
The effects are slow and subtle, and therefore they are so damaging.
Let me explain:
As a human being, you don't see the grass growing--you just notice that the grass has grown tall over a couple of days...
Likewise, you don't observe air pollution damaging you like you the obvious problem that emerges if you break your leg...
(10 additional solutions are included in the full blog post).
"You need to filter the air, human? Weirdo!"
Again, ten other pollutant-lowering solutions are included in the full blog post.
First, get a rough estimate via a nearby measurement in on the World Air Quality Index. Secondly, either get a budget measurement device or a higher-quality one to measure air pollutant levels in your home and workplace.
While these measurement devices don't measure all air pollutants I've included in this blog post, the particulate matter that's measured by the device above can act as a proxy for many other pollutants.
That method gives you a much better picture than going off feeling or local air quality maps.
Ready to get the full picture?
Here we go...
Read the full blog post below
Save to Pinterest:
1. Carbon Monoxide (CO)
2. Nitrogen Dioxide (NO2)
3. Particulate Matter
4. Volatile Organic Compounds (VOCs)
5. Ozone (O3)
6. Sulfur Dioxide (SO2)
7. Biological Pollutants
8. Radon (Rn)
9. Carbon Dioxide (CO2)
10. Toxic Mold
12. Heavy Metals: Airborne Lead And Cadmium
13. Nerd section: Solar Wind And Flares From Space
1. Ventilate Your Indoor Environment
2. Avoid Heavily Air Polluted Areas
3. Use An Air Purifier
4. Use A (HEPA) Vacuum Cleaner
5. Insulate Your Home To Decrease Ventilation
6. Alter Building Construction To Reduce Radon Exposure
7. Eat A Healthy Diet
8. Buy Healthy Furniture, Household Products, And Paint
9. Avoid Damp, Water Damaged, Or Moldy Environments
10. Control Indoor Humidity And Temperature
11. Use Both Indoor And Outdoor Vegetation
12. Wear A Respirator If You're Exposed To Air Pollution
13. Build Resilience With Exercise
14. Avoid A Completely Sterile Environment
15. Consider Your Personal Susceptibility To Air Pollution
*Post can contain affiliate links. Read my affiliate, medical, and privacy disclosure for more information.
Author: Bart Wolbers. Bart finished degrees in Physical Therapy, Philosophy (BA and MA), Philosophy of Science and Technology (MSc - Cum Laude), and Clinical Health Science (MSc).
Let start on a little detour - you understand what I'm getting at regarding air pollution very soon.
I'm going to talk about facing the reality of an obvious problem first.
And you know what?
you may be working at an internet company that has losses quarter after quarter, and yet, everyone working there is acting like it's 1998 - having that cheerful attitude they had at the height of the internet stock bubble.
a friend of yours, who has smoked for 30 years, has been coughing for a few weeks now. He tells you: "maybe it's the colder weather that's causing these lung problems?"
your colleague claims to be so busy that she doesn't have time to meet up. But you know that she's spending 6 hours a day on her smartphone and in front of a television.
it's now 10 years since the world has experienced the last global recession. And yet, government projections, companies, and consumer sentiments all assume that the party will continue for several years (and up to a decade)...
The master of the house: another elephant
in the room that's rarely acknowledged...
Acknowledging an elephant in the room takes guts.
But let's face it:
Many people living in the city are confronted with such an elephant every day...
You may be too.
Air pollution is like an elephant.
A huge pink elephant. Everyone just knows that elephant exists.
Let me tell you why - I'll give an analogy:
Most people know they should exercise, and for that reason they do. If I were to make a rough guesstimate, about 60% of people in my country (the Netherlands) exercise in one form or another.
Many people also know they should watch their diet, and for that reason, they do. To be more precise: most health-conscious people intentionally avoid eating at McDonald's or Burger King 6 times a week.
In the case of air pollution, however, a switch is triggered.
Let me explain:
Ask the fitness addict who spends 5 evenings a week in the gym and watches her diet meticulously what she does to lower her exposure to air pollution. Or go to a health store and ask the owner what products he's offering to counter air pollutants.
You'll be met with a blank stare...
So ask yourself this simple question:
My rough guesstimate is that two percent of health-conscious people watch their air pollution levels - at the maximum.
And yet, if you care about your health you should care about air pollution.
Let me tell you why:
Sure, most of these deaths occur in Asia, but even developed countries have air pollution levels that negatively affect your health no matter where you live.
It may sound counter-intuitive, but even in the developed world hundreds of thousands of people still die due to air pollution's effects.
And no, not every decade but every year...
Of course, there are many different causes of air pollution, such as aerosols from sprays, natural causes such as forest fires or volcanoes, indoor cooking that "kills" air quality, gases, and tiny particles emitted by car or airplanes, and industrial output...
I'll treat all these causes in a subsequent section...
They key is to realize that all these air pollutants place a tremendous burden on your health.
Think about it: 8 million, that's a lot of people dying each year because of the direct effects of air pollution...
Of course, I'm not arguing that more people should die. What I'm saying instead is that the statistics are short-sighted.
Let's return to the figure of 8 million "deaths" per year. A death occurs when someone dies while being able to live many more months or years.
Besides the 8 million yearly deaths, at least 100 times as many people's health is negatively affected.
Even if you don't die, air pollution thus still worsens your health.
If I die in 10 years due to an accident (hopefully not), and I've breathed polluted air for 42 years by then, air pollution has still negatively affected my health over that period.
It's also very likely that you, the reader who's living in a developed country is not going to die directly from air pollution.
And yet, your heart and lung health will be negatively affected by dirty air.
(most of my readers come from developed countries right now).
That's bad news...
Immediate perception does not always match reality.
The same is true for air pollution: the problem is worse than you think.
Let's explore why air pollution is so under-emphasized:
The stuff you're breathing is like an imperceptible poison drip.
Just imagine that each day, your "loving" partner adds a little bit of arsenic to your meals. Arsenic is a poison and does not have any taste or odor, but you'll start feeling pretty bad once you ingest too much of the stuff.
Over time, even though your partner creates "wonderful" meals for you, incredible damage is being done.
Your health deteriorates imperceptibly and in time you'll start thinking that you're struck by fate.
Of course that conclusion is completely wrong, but still, if you do think you had "bad luck" you may assume that there's nothing you will do about that situation.
Then your helplessness starts...
The analogy here is that air pollution's health effects are also imperceptible. Due to that imperceptibility, most people are not consciously aware of the air they're breathing--unless, perhaps, they already have lung problems.
That's bad for you, as damage is being done even if you don't think there is.
I'll tell you...
Don't worry: I'm not preaching despair...
On the contrary:
To experience these benefits though, you do need to take action.
To be more precise: you need to take action...
Don't wait for:
But let's consider why you should not wait for governments and (international) institutions to reduce the health effects of air pollution for you first...
A worldwide campaign has set a goal of halving air pollution deaths worldwide by 2030. Halving air pollution deaths still entails that 4 million people are being killed on a yearly basis.
Many international treaties also tragically fail.
Consider the eight "Millennium Development Goals" that were set in the year 2000 for 2015. The only reason the poverty reduction goal was met is because of China's rapid economic development during that period.
Government policy had little to do with that accomplishment--more free markets did.
And even if governments and health institutions succeed in their goal of reducing air pollution by half, you'll still be exposed to dangerous levels.
An additional valid argument exists, however, that tells you why you should not wait for governments to rescue you:
Reducing air pollution directly hurts economic development. Don't believe me?
Consider these examples:
Let's say you:
There's no clear incentive to fully eliminate the problem of air pollution (yet)...
(Nerd section: from an economic standpoint, the example given above is oversimplified. The health gains due to lowering air pollution also has advantages such as increased productivity and saving healthcare costs. In the short-term, however, pollution probably maximizes economic growth.)
Again, keep in mind that I'm not trying to make you depressed.
There's good news too:
Air quality has been improving in most of the developing world. Society-wide improvements in air quality are thus possible. Take a look at the levels of common air pollutants that are emitted in the United States:
(Ammonia levels are not correctly displayed)
Sulfur dioxide emissions have gone down 90%, and tiny particles numbers that are created as a byproduct of industry or transportation (PM2.5 and PM10) have almost halved.
(I'll tell you more about these pollutants in a moment...)
And there's more good news:
Sure, in absolute terms--because these countries' populations are growing--air pollution takes more lives than ever. Quantified as years of life that are lost per 100,000 inhabitants, however, deaths due to air pollution are going down.
But again: today air pollution levels are still negative for your health, and in 2030 the same is expected to be true.
A decline is not enough to save yourself--you'll want to minimize your exposure.
My goal with this blog post on air pollution is two-fold:
The previous installment of this series treated the topic of "particulate matter". In that guide I claimed that you could reduce the negative effects of exposure dramatically by implementing a few solutions in your life, such as using air purifiers, planting vegetation, and avoiding "hot spot" locations of particulate matter.
Many of these solutions will return later in this blog post - in the fifth section I'll give you fifteen different solutions to reduce your inhaled level of air pollutants.
But first I'll tell you about the history of air pollution. The reason for including that history is that many people think that our ancestors were also exposed to toxic air every day.
Nothing could be further from the truth.
Let thus go back in time:
Contrary to popular assumption, the negative health effects of air pollution didn't originate in the 19th century for us humans...
During the 19th century Industrial Revolution ithe number of factories grew exponentially, creating air pollution en masse (assuming accept that there was such a "revolution" historically).
You can, for example, even make claim that dinosaurs became extinct because of air pollution.[5-8]
66 million years ago a meteor 6-9 miles in diameter hit Mexico, creating the Chicxulub crater. Dust enveloped the earth as a result of the meteor impact (together with similarly timed volcanic eruptions) and cooled down the planet.
(Non-flying) dinosaurs were dependent on external heating from sunlight and could no longer survive.
75% of all other species went extinct as well. The health effects of air pollution are thus as old as this planet...
A cutie who was killed by air pollution...
There's yet another reason to assume that air pollution arose much earlier than the 19th century:
The discovery of (intentionally using) fire occurred about 800,000 years ago, and our human species originated ~200,000 years ago.
Keep in mind that thus our it's your human-like ancestors - commonly called hominins - who learned to control fire first. Hominins are millions of years old
That control of fire does not exclusively have beneficial health effects. The obvious downside is that air pollutants are created.
The upside, of course, is that fires generates lots of heat. That heat helped our ancestors survive in colder environments such as Northern Europe.
But remember the dates I just gave you?
Essentially, the brain development of our ancestors started millions of years before the discovery of fire-control. During most of our hominin history air pollution was thus absent, except the pollution created by natural causes such as volcanoes and forest fires.
Let me give an example...
After the discovery of fire, fireplaces were used in caves. Fires in caves implies that your ancestors also exposed themselves to air pollution from that fire - smoke is very difficult to remove from caves.
Fast-forward a few million years:
Of course, indoor fire was also used as heating sources, especially in colder areas of the globe.
The bad news?
Indoor cooking dramatically increases the air pollutants levels you're exposed to compared to creating fires outside.
It's thus simple to conclude that air pollution did thus not start in the 19th century...
Other air pollution sources existed back then as well though. If you were a smith who was working bronze or iron, you'd be exposed to other toxins such as heavy metals.
Lead, a toxic heavy metal, was also used in construction and to preserve wine. Smelting that lead would have negatively affected your health, even though people didn't know about lead's harmful effects (yet) back then.
Air quality was surprisingly considered important back then, even though people did not fully understand why.
A "Hearth" was invented, a central fireplace inside a home with an open hole in the roof so that most smoke could exit the building without polluting the entire room. Chimneys that direct the smoke directly away from the indoor environment were only invented in the 12th century.
A late-medieval hearth in an "upper-class" household
with a chimney.
The indoor usage of fireplaces remained relatively primitive well until the 18th century. For most of humanity's written history, indoor air pollution has thus been "part of the deal".
Only in the late 19th century, with the invention of electricity, was it no longer necessary to have a fireplace in each house for food preparation and heating.
A French chemist called Antoine-Laurent de Lavoisier discovered (and named) oxygen as one of the gases that are subsumed in the air.
Before Lavoisier, other chemists had already discovered that there was no "uniform compound" which is "air". Instead, chemists knew that air actually is made up of several individual substances.
During the chemical revolution, different chemical elements were measured and categorized, which led to the possibility of studying individual substances subsumed into that air. In turn, that chemical revolution indirectly gave rise to the possibility of actively controlling that air...
A full understanding of air pollution, however, only developed slowly: the pollution problem became (much) worse before it got better. While some problematic periods of air pollution existed in big cities such as London between the 16th and 18th century, the air pollution problem really took off after that time.
Factory air pollution was unregulated at the beginning of the 20th century. That changed with a few developments in the 1950s and 1960s, when the harmful effects of air pollution became completely undeniable.
The great smog of London in 1952, during which lethal levels of sulfur dioxide were emitted into the air, killed a total of 10,000 people and made 100,000 ill. That smog led to the first wave of air quality regulations.[16; 17]
In 1962, a book called "Silent Spring" by Rachel Carson subsequently made the world aware of the side-effects of pesticide use.[18; 19]
Pesticides are also (partially) spread through the air...
From the 1950s and 60s of the 20th century, humans became painfully aware that their living environment did not just revolve around the house they were living in--the factory nearby, pesticides sprayed on your food or into the air, and traffic could poison the air you're breathing so that your health was affected.
Most people have nonetheless remained very complacent in controlling the air quality in their environment. From the 50s up until today, almost everyone assumes that air pollution is the government's task to deal with, not your individual responsibility.
(Hopefully that attitude will change after you read this guide)
Ask any kid whether he considers smoking or breathing in car exhaust is healthy, and (s)he'll answer "no".
Two hundred years ago, people didn't know that air pollution was (that) damaging.
A simple analogy to understand that absence of knowledge can be made to bacteria and viruses: before the mid 19th century, medical practitioners were not aware of hygiene's importance, nor were bacteria or viruses identified separately.
Initially, viruses were even presumed to be the same thing as bacteria--until scientific experiments proved otherwise. That distinction between viruses and bacteria nevertheless took time to be accepted by the scientific community.
The same is true for understanding air pollution...
Understanding of air pollution's health effects only slowly developed through the last few decades. That development is not done today, as new studies keep emerging. In some ways, air pollution is still misunderstood by the general public.
In developed nations, most people now assume that air quality is a problem that's located outside their homes. Scientific reality, on the contrary, shows that indoor air quality matters as much today as it did during (pre-)history.[13-15]
In most cases, outdoor air pollutants simply enter buildings but never leave.
Talk about an unwelcome guest...
Let's therefore quickly determine whether you're affected by indoor air pollution as well. Consider this simple test:
If you answered "yes" twice, then congratulations: you can improve your health without having to spend thousands of hours in the gym, because indoor air pollution can be relatively straightforward to deal with in many cases.
In fact, simply integrating the solutions I'm suggesting later on in this blog post (section five) will guarantee improvement.
Let's, therefore, start digging into the problem of air pollution...
Oh, one last thing:
That's a great question, actually, but my answer to that question is a resounding "no".
Consider exposure levels of "sulfur dioxide", a common byproduct of industrial processes that's emitted into the air:
As you can see, sulfur dioxide levels were pretty low before the 1850s compared to the late 20th century.
99% of sulfur dioxide contained in the air today ended up there because of human action. So no, nature herself does not put extreme amounts of sulfur dioxide into the air (for longer periods of time).
Additionally, air pollution is also unhealthy, even when coming from natural sources. Air pollution should thus not be accepted as a given.
And of course, before the Industrial Revolution coal was also burned in homes - creating a sulfur dioxide problem. Nevertheless, the quantities emitted into the air only became extreme with the emergence of the factory system and mass burning of fossil fuels.
You're thus at greater danger today than in 17000, although the nature of your exposure has changed.
Again: you'll want to lower your exposure...
In the next section, I'll look at thirteen different types of air pollutants and their health effects.
Fasten your seat belt, because that section is going to be somewhat depressing...
Before diving deep into the effects of these many air pollutants, let's grasp two basic air pollution principles first.
Particulate matter, which are tiny particles that emitted by cars and industry, can be created in the atmosphere by reactions of other types of air pollution that ended up there.
An air pollutant called "ozone", can be created when car exhausts react with sunlight. Air pollution can thus exist of chemicals that react within a given environment and create new types of air pollution.
Then there's another important basic principle:
The weather can thus determine how much air pollution ends up at your doorstep, not only by creating new types of air pollution but also by steering their trajectory so that they end up in one place rather than another.
Instead, just get a general impression of these air pollutants - you don't have to understand their ins and outs completely to adequately deal with them.
Of course, if you're interested then read the full sections. To be honest, the solutions given later are more important:
In section five I'm going to break down the solution to lowering your exposure to these toxins in very simple to follow steps. These steps to reduce air pollution levels will work regardless of whether you understand the intricate details of all air pollutants in this section.
As of this moment, this guide is already over 25,000+ words long. If I had included all important air pollutants and described their full effects, not even 2,500,000 words would not have been sufficient.
Let's now take a deep dive into thirteen different air pollutants. I'll start with an air pollutant you're may be acquainted with:
Carbon monoxide (CO) is a gas. CO is deceptively dangerous because it cannot smelled or seen.
Carbon monoxide is created when carbon containing compounds (such as gasoline or coal) are incompletely burned, due to insufficient available oxygen being present. You probably know that "carbon dioxide" is normally created, instead of "carbon monoxide".
Let me explain:
Just imagine burning wood at a fireplace that does not have enough access to fresh air. Over time, oxygen levels around the fireplace will go down. The burning of wood that ordinarily results in "carbon dioxide" will then off-gas "carbon monoxide".
Cozy fireplaces: deceptively dangerous...
Most carbon monoxide (CO) is created by human action.
If you drive a car or truck or work in an industry where fossil fuels are used, small amounts of carbon monoxide can be emitted continually into the air.
Indoor sources of carbon monoxide exist as well.
Smoking is a common reason for inhaling carbon monoxide - from both cigarettes or water pipes. Second-hand smoke is another reason you're being exposed to CO.
You see, the role of hemoglobin is to transfer oxygen in your blood.
Under the influence of carbon monoxide, that hemoglobin is transformed into something called "carboxyhemoglobin", making the hemoglobin compound impotent. As a result, your blood can no longer properly carry oxygen (and carbon dioxide).
The consequence is that the oxygen that you breathe through your lungs--that is normally diffused into the bloodstream--can no longer be used. Your body's cells end up no longer functioning adequately.
In worst case scenarios you can even die of the consequences of CO poisoning.
You don't initially notice that you're breathing this compound, and may fall asleep (and die because of the body's inability to regulate itself in sleep).
Over time, you may notice symptoms of CO poisoning.
These symptoms can include headaches, mental problems (confusion or poor memory), nausea, dizziness, and overall bodily weakness. You may also have a low heart rate or low blood pressure, poor coordination and less of an ability to speak clearly.
CO Is currently responsible for 50% of fatal poisonings in the world.
Carbon monoxide also influence how well your mitochondria function.
Mitochondria are the energy-producing factories in your cells. While I'm oversimplifying, oxygen and food are transformed into water and carbon dioxide in the mitochondria. In essence, the process that's present in plants by which plants create oxygen from carbon dioxide and water is reversed in your mitochondria.
Carbon monoxide thus short-circuits that process in your cells as well so that they can no longer function adequately.
And there's more bad news:
And it's not just the severe cases of carbon monoxide poisoning that you should worry about.
Smaller exposures matter...
Remember that the exhausts of cars and trucks produce carbon monoxide. Many people are exposed to that pollution without ever nearing the threshold of full-fledged carbon monoxide poisoning.
In other words, if you're being exposed to small amounts of carbon monoxide every day you probably won't notice any symptoms, but your blood will still carry less oxygen and the energy creation process in your cells will be sub-par.
If you're spending lots of time inside vehicles, you're going to be exposed to more carbon monoxide.[32-35] That car exhaust can significantly lower your blood pressure, for example.
Just spending time outside in bigger cities with lots of cars increases your carbon monoxide exposure as well.
Lawn mowers, leaf blowers, electricity generators that work on fossil fuels, etcetera. Indoor carbon monoxide sources are air conditioning systems, (central) heating, and generators.
Indoor cooking in developing countries also produces carbon monoxide, which may increase blood pressure. The reason for that carbon monoxide creation is that indoor levels of oxygen tend to go down if you cook indoors.
But let's explore CO's health effects in more detail...
Yes, overall that's very bad news. Carbon monoxide is thus not "innocent"...
If levels increase by 1mg per m3 then a city about 1% more people will die of heart disease and strokes over time - other studies show an even bigger effect.
If you've already got heart disease, lung problems, anemia (low iron in your blood, which already gives you an inability to transfer oxygen well), have multiple diseases, or if you're of young or older age, then carbon monoxide will affect your health even more than normal.
Short-term exposures of carbon monoxide can thus put you "over the top" if you're already sick.
Delicious sight--but not enough oxygen present
to prevent carbon monoxide buildup?
Brain recovery and increased diabetes risk, while sometimes taking years of time, are possible. Unfortunately, stroke risk and heart disease risk do appear to remain higher over time.[51; 54; 55]
Really low levels of carbon monoxide exposure might be beneficial to your health, as there's an adaptive response to exposure.
Don't stress out too much about carbon monoxide right now. Remember: in a later section I'll teach you how to avoid the worst pollutant levels...
Let's move on:
You'll now learn about an air pollutant that most people don't know about, nitrogen dioxide:
Just as with carbon monoxide, fossil fuel usage is one of the main reasons nitrogen dioxide emissions exist in the first place. Most nitrogen dioxide either originates from traffic emission or power generation (and use).
Industry or agriculture does not emit large quantities of nitrogen dioxide (although they do emit other nitrogen substances).
Nitrogen dioxide is part of a group of substances called "nitrogen oxides" (NOx). Nitrogen dioxide is the most important type of NOx, and to keep the message relatively simple I'll, therefore, focus on nitrogen dioxide in this blog post.
At higher concentrations (for nerds: 200 micrograms per cubic meter (m3)), nitrogen dioxide is directly toxic.
Not fun, that list...
Let me give you a perspective of how damaging NO2 is:
In Germany, it's estimated that up to 8% of all diabetes cases are directly caused by nitrogen dioxide - equaling nearly half a million people.
That figure alone also tells you why air pollution is not a problem you can choose to ignore if you care about your health.
Another example: over 20,000 people die in the United Kingdom because of this air pollutant on a yearly basis.
Why are the effects of nitrogen dioxide not widely known?
Well, for a long time it was hard to distinguish between the effects of nitrogen dioxide and particulate matter - both air pollutants are co-created in large quantities in modern society. And now the extensive effects of this pollutant are correctly understood, it's time to get more worried...
One very common source of nitrogen dioxide exposure
- an example of air pollution's poison drip...
More bad news:
Children, elderly people, and people with pre-existing lung or heart problems are hit hardest by exposure to this air pollutant (again).
If you've got lung, airway, or breathing problems, inhaling nitrogen dioxide can exacerbate your symptoms, such as causing an increase in coughing, wheezing, an increase in mucus production, or breathing problems.
When emitted into the air and reaching the atmosphere, NO2 can also react with other chemicals which leads to the production of new air pollutants.
In fact, two air pollutants that can be created through reactions with NO2 are next on the list: ozone (O3) and particulate matter.
The next air pollutant should create an even bigger incentive you to take air pollution seriously:
So let's consider particulate matter: the "king of air pollutants"--or maybe "most tragic air pollutant" is a better name...
Particulate matter are tiny particles subsumed in the air that are created as a byproduct of traffic, energy production, cooking, and industry.
Due to particulate matter's heavy impact on human health, I've written an extensive blog post (or guide) on the topic before. That guide teaches you how to reduce your particulate matter exposure by 50-90% - even while living in the city.
But let's talk about that stuff quickly:
Particulate matter is commonly measured by size - specifically the "micrometer" metric. One micrometer is a thousand times as small as a millimeter - yes, that's really small.
The problem is that these tiny particles end up in your lungs, your bloodstream, brain, and organs. Once particulate matter enters your body, the damage begins.[183-190]
Different types of particulate matter exist.
Common measurement categories for particulate matter are:
To put these numbers in perspective: the average human hair has a diameter of 70 micrometers...
2.5 micrometers or 0.1 is thus extremely small and invisible to the human eye.
The smallest type, PM0.1, may even be able to travel directly from your nose to the brain.
It's often hard to imagine that particulate matter has negative health effects, so let's consider the following analogy:
Most people can imagine that if billions of harmful bacteria are breathed in, that they can be harmful to your overall health. In the case of particulate matter, you can simply imagine that tiny dust particles end up everywhere in your bloodstream, brain, and other organs.
In fact, dust often consists of particulate matter so you don't need to think very far outside the box to understand the effects particulate matter has on your health.
There are many...
(Many more effects are laid out in my extensive guide on particulate matter.)
Children, elderly, and people with pre-existing lung or heart conditions are hit the hardest by particulate matter (yet again).
While short-term exposures to particulate matter already cause adverse health effects, such as an increase of stress hormones and blood pressure, the negative health effects of particulate matter accumulate the longer you're exposed.
The last two air pollutants I've discussed (particulate matter and NO2) are mainly found outdoors. The next one is found is found everywhere:
Volatile Organic Compounds or "VOCs": that sounds like a complicated word.
No worries thoguh...
Simply put, VOCs evaporate into the air...
VOCs can be created from several sources, such as a byproduct of the burning of fossil fuels or as an off-gassing of chemicals such as solvents.
Sources of VOCs are oil and gasoline that are burned by cars and airplanes, as well as fossil fuels used in energy generation (e.g. power plants).
Coatings, varnish, glue, adhesives, and paint are common VOC sources. Plywood, vinyl flooring, and particleboard are also problematic off-gassing causes. Additional sources are cosmetics, aerosol sprays, air refreshers, cleaning products, and disinfectants.
Plastic materials in kids playing toys? Toxic VOCs.
Getting your hair colored in a salon? More VOC exposure...
That new car smell? That's VOCs being emitted from the interior.
Incense burning or indoor smoking? VOCs...
Buying a new dinner table, sofa, carpet, or cabinet? That furniture is coated with VOCs to preserve the material and make it look shinier.[149; 151; 159; 160; 162; 165]
A beautiful new painted or coated cabinet will release new gases into the air over the course of years.
How about outdoor VOCs?
Benzene exposure when refueling your car tank, or the exhaust you're smelling when using your lawn mower are common sources.
Counter intuitive VOC indoor air pollutants from chairs,
cushions, and the couch...
Simply put, VOCs are gases that are emitted from many compounds humans have introduced to the environment.
Unfortunately, not all VOCs are easily measurable, so the scientific understanding is still incomplete.
The levels of one VOC called "formaldehyde" can be easily estimated, for example. The problem is that thousands of different types exist, which are sometimes hard to measure. New VOCs are also identified over time...
And it's not just breathing that's problematic--VOCs also enter the body through skin exposure.[178-180]
It's safe to assume that less exposure is better.
(Nerd section: It's not probable that short-term exposure to VOCs is very damaging. The problem starts with longer-term exposure. Additionally, a problem with mapping the health consequences of VOCs, however, is that they are a very broad category that tells you almost nothing about the effects of individual toxins. Some VOCs have been proven to be highly damaging, such as formaldehyde, while many other VOCs have yet to be identified. Data on exposure patterns of different types of VOCs is also limited compared to previously treated pollutants. The topic of VOCs is extremely complex, as toxicology and exposure patterns of thousands of chemicals as well as their interactions would need to be mapped to attain a complete understanding.)
An example of a VOC?
Benzene is a natural part of crude oil.
When you're filling up your gas tank at the gas station, you're being exposed to benzene if the wind is blowing in the wrong direction (at you). Forest fires, volcanoes, and cigarette smoke are other benzene sources.
As a VOC, benzene has many different health effects.
At low levels, benzene causes throat irritation, trouble breathing, skin rashes, eye irritation, increased blood pressure and confusion. [240-243] At higher levels, benzene increases risk for leukemia (cancer of blood and bones), especially in children, but can also cause kidney and liver problems - and finally even death.[237-239; 244-247]
And although my treatment of benzene is really superficial here, fully considering its effects of different all types of VOCs is impossible in one blog post.
And remember: even though this list may seem overwhelming, I'll tell you all about simple solutions later on in this blog post.
Stay with me...
Next, I'll consider an air pollutant which many people living in the 70s and 80s are acquainted with:
You probably know about the chemical structure of the oxygen you're breathing (O2), which contains two oxygen atoms.
(Both the atoms of the substance that you're breathing, as well as the compound gas itself, are thus problematically called "oxygen".)
A compound called "ozone" also exists, which contains three oxygen atoms (O3).
When present at the earth's surface, that ozone is often considered a pollutant. Nevertheless, ozone is also essential for life to exist at this planet at all: in the atmosphere, ozone filters out excessive radiation from the sun.
That ozone in the atmosphere is called "stratospheric ozone". The emission of several air pollutants into the air can damage that protective "ozone layer", but fortunately, that layer is slowly recovering.
Ozone emissions have been going down the last few decades--this air pollutant is thus currently less damaging than it was 30 years ago. Bright spot: again, humanity can improve the environment.
The protective ozone layer is found
20-30 kilometers up in the sky
On the earth's surface (where you're living unless you're an astronaut), ozone is mainly created through the reactions of other chemicals.
To be more precise:
Remember that VOCs and nitrogen oxides (NOx) can be created from many sources, such as exhausts of vehicles that burn fossil fuels, as a byproduct of energy creation, industry, and others.
Even though many previously treated pollutants are more problematic in colder environments because they are more prone to keep on "hanging" in the air, that's not true for ozone - sunlight is essential to ozone creation.
Not all ozone is created by humans though: a greenhouse gas called "methane" is a natural source for ozone when it reacts with sunlight.
Small amounts of ozone are generally considered safe, but in larger amounts, negative health effects begin to appear.
You might be thinking: "so what are the health effects of ozone?"
Fortunately, the effects of ozone exposure have no (proven) effect on your mental health, such as autism, dementia, or decline in thinking ability (cognitive functions). Your overall risk of death, surprisingly, is not affected by both short-term and overall yearly ozone concentrations either--although there's some conflict of evidence regarding this point.
If you have pre-existing lung or heart conditions ozone will also affect your health more negatively.
Even if you're healthy, you should still be wary of ozone exposure because of its effects on the airways. Your propensity for shortness of breath, wheezing, coughing, and inflammation increases - of course, this process occurs more frequently if you've already got lung problems.
Although there's some contradictory evidence, some studies suggest that your lungs and heart simply have to work harder when you're exposed to ozone.[137-141] Longer-term exposures at higher concentrations are most likely harmful.
Current safety threshold set by institutions such as the US Environmental Protection Agency may not be low enough to prevent harm to those who are more susceptible to ozone's damage.
Previously treated air pollutants such as particulate matter and nitrogen dioxide are much more damaging than ozone.
To reduce exposure, be very wary of any indoor ozone generating products. Some air purifiers, for example, sometimes generate ozone as a byproduct or even intentionally emit ozone into the air.
Ozone may be helpful in certain instances, such as reducing the toxins of household items that have collected mold on them--but it's recommended to be extremely cautious with exposing yourself to ozone if you don't know what you're doing.
(Nerd section: keep in mind I'm not in favor or against what is called "ozone therapy". Ozone therapy seems to elicit a hormetic reaction in the body, and may or may not have health benefits - I've not closely looked at the evidence yet, so I cannot judge. )
Next, let's consider sulfur dioxide - the air pollutant that was primarily responsible for the great fog of London in the 1950s, which started a wave of air pollution control legislation:
Sulfur dioxide is actually one of the longest tracked air pollutants.
The reason for that relationship is that sulfur dioxide is a direct byproduct of energy production from coal.
Coal: humanity's angel and devil at the same time.
As coal was used on a larger scale after the Industrial Revolution, nations began to track their coal production and consumption. From that data it has now become possible reconstruct how much SO2 pas put into the air over the last few centuries.
The reason sulfur dioxide emissions were reduced in Europe and North America after the 1970s and 80s, is because SO2 lowering technologies were mandated for energy production industry such as coal plants.
Even in some Asian countries such as China, SO2 emissions are declining today. India, however, still increases its yearly emissions, which is why overall Asian SO2 emission increase.
When sulfur dioxide is emitted into the atmosphere, chemical reactions can also help it turn into particulate matter. Acid rain can additionally be created through sulfur dioxide exposure, so the pollutant has a negative effect on the environment.
Your neighbor is thus not always your best friend when sulfur dioxide emissions are in play...
Next to sulfur dioxide, other sulfur gases such as SO3 are also harmful. I won't cover these other sulfur compounds in order to not complicate this blog too much...
Having said that, I'll now move to the next category of pollutants: air pollutants with indoor origins (most of the time):
Let's start with a definition: biology is the study of living organisms. All air pollutants included in this subsection are thus (derived from) living beings.
I'll consider several biological air pollutants, such as allergens including pollen, animal dander, and dust mites.
If you're having an adverse reaction to biological pollutants, many of the symptoms overlap with what you'd get from exposure to air pollutants such as sulfur dioxide or particulate matter:
Stronger reactions entail having headaches, becoming ill, dizzy, or depressed.
Of course, exposure to germs can have more far-reaching consequences.
Some people's immune system responds very heavily towards certain substances entering their bodies. If your immune system reacts very heavily over and over again, you'll feel the consequences - resulting in the symptom list I described above.
You may know someone with allergies: they'll get sick if they eat peanuts or drink milk. You also know some people who are completely unharmed when consuming milk or peanuts - signifying an absence of allergies
So what's up with allergies, and the substances causing these allergies called "allergens"?
Pollen should not be considered an "invader" to your body but can be treated as such if you're allergic. Pollen are emitted into the air by plants and act as a fertilizer for plants of the same species. These pollen can travel hundreds of miles...
When pollen are reintroduced into the air in the spring at many locations, for example, asthma attack numbers increase, .
Different people are allergic to different types of pollen. You may be intolerant to the pollen of certain grasses, or to pollen of beech trees while having no problem with grasses at all.
(Keep in mind that in this blog post I'll only consider substances emitted through the air, and not food allergies.)
The result for (some) poor humans?
If you're breathing these substances while allergic, signaling substances such as "histamine" are created as a response to the allergen exposure, and bodily inflammation is increased.
Springtime: not fun for everyone...
A surprise about allergies?
Contrary to 50 years ago, allergies are really widespread today: up to one in four persons has hay fever in developed countries. 40 to 50 million people have one allergy or another in the US alone,
And you know what?
Allergy risk increases by exposure to lots of (smaller) particulate matter and dust mites (a topic I'll treat in a second).[314; 315] Particulate matter exposure also worsens existing allergies.[317-319]
In fact, indoor pollutants pose the biggest risk factor for developing allergies. Suddenly those omnipresent VOCs no longer sound so smart. Many "regular"air pollutants thus contribute to your risk of getting allergies to biological substances.
But let's move to the next biological air pollutant:
A sad development, all these allergens--as if human-made air pollution weren't menacing enough...
And you know what?
Many traditional societies don't have a conception of allergies at all.
Hay fever was extremely rare in the late 19th century. Specific diseases that are highly interrelated with allergies such as asthma only became more prevalent after the 1960s.
"Coincidentally" (or not so coincidentally), the number of allergic people has massively increased since humans adopted an indoor lifestyle.
Spending lots of time indoors thus has its expected downsides...
By the way:
Let me explain why:
On the one hand, germs have made human lives miserable and short for thousands of years - they're thus really important.
Tuberculosis incidences, for example, which are caused by bacteria, are dramatically influenced by air quality. Influenza is another example that's widely known as a pathogen that's carried through the air.
On the other hand: humans have always been exposed to germs. Germs are thus very different than many types of modern air pollution, in that continuous air pollution is novel from an evolutionary perspective.
Even biological types of air pollution such as the dust mites and cockroaches stand in a totally different relationship to you today than 200,000 years ago when your ancestors evolved in Africa.
That's why I excluded germs here...
Next, another indoor air pollutant:
Back to the topic of gases: radon (Rn) this time.
Remember that I've considered other gases before, such as carbon monoxide (CO).
And just as is the case with carbon monoxide, it's impossible for you to smell radon. And likewise to carbon monoxide, the only way to know you're exposed to radon is to measure.
How does that happen?
Well. radon is created when uranium decays.
Radon can be found in homes, offices workplaces, and public buildings, but is not found outside homes in any large concentrations.
Radon quickly dilutes in outdoor air.
Cracks in the floor, spaces around pipes that have not been sealed, and holes in walls are mechanisms by which radon "sips" into buildings. Good isolation of ground floors of buildings ensures that less radon is passed from the basement or crawl space into the actual building.
Basements generally get high radon exposure. Other underground locations such as caves and mines are especially dangerous for radon levels - unless they're properly ventilated.
Poor ventilation "entraps" some of the radon in buildings, resulting in negative health effects.
Radon has only become problematic is (again) because humans have have moved indoors while insulating their buildings so that little air can enter from the outside.
If you're thinking: "am I at risk", then here's the answer:
You can guesstimate your exposure levels with the following maps:
Don't use that map to speculate about your specific living locations' radon levels though, as two houses located 100 yards apart can have hugely different exposure levels.
On another note...
Want to know a shocking radon fact?
Here it is:
The risks of these two dangers stack: if you're already smoking then radon exposure will further increase your cancer risks.
Up to 10 times as many smokers die of radon exposure compared to non-smokers. Smokers also have up to 25-times higher risks of dying of radon-induced lung cancer than non-smokers.
There's no radon exposure "safe zone" regarding lung cancer risk--less exposure is always better, even if you don't smoke.
Unfortunately, the research in these non-lung-cancer health domains is not crystal clear yet. It's thus essential to wait for more high-quality research to be released on those topics.
The relationship between radon and disease is fascinating to me because it's reasonable to assume that radon exposure does cause additional health problems next to 20,000 yearly lung cancer deaths (in the US alone).
In the case of particulate matter, many health effects were also discovered in time. I expect radon to follow the same pattern (to a lesser extent) as well...
Furthermore, radon can also end up in your drinking water.[73-74] It's uncertain whether radon in drinking water has health effects though, as exposure has negative associations with stomach cancer, for example.
Putting that number into perspective: drunk driving kills 17,400 people each year, drownings 3,900, and home fires "only" 2,800.
Radon air pollution is not part of the common awareness (yet again), the problem is therefore not actively tackled actively.
But enough about radon...
The next air pollutant is carbon dioxide. You probably know that compound from biology class:
Carbon dioxide is often considered an environmental pollutants--but its true status is more complex - even in your body.
I nevertheless subsume carbon dioxide under air pollutants because high indoor CO2 levels are often a culprit why people function poorly. Let's start with a comparison to understand high CO2 levels in indoor environments.
(Outdoor CO2 levels have been creeping up due to climate change. CO2 levels used to fall below 300 parts per million in the 19th century.)
That's where you get into trouble.
A well-ventilated indoor environment contains up to 1,000 parts per million CO2. But: that 1,000 parts per million almost triples "nature's normal levels" alrady.
And the story gets worse.
Indoor environments such as offices and classrooms can contain levels up to a whopping 5,000 parts per million of CO2.
In the wintertime, classrooms in temperate climates generally have CO2 levels between ~600 and 4,000 parts per million. During the summertime that levels decreases to ~500 to 2,000 parts per million.
Less ventilated a building build up more carbon dioxide. Let's now first consider the problem with too much carbon dioxide.
In general, your health immediately declines slightly once your spending time in a room where CO2 levels approximate 1,000 parts per million.
Getting a good ventilation system in place is one method to keep CO2 levels low. In fact, optimizing CO2 levels is highly underrated for improving indoor air quality (and well-being).
That's it for CO2.
Now I'll tell you about one of the most toxic indoor pollutants - in many instances this one should make you run, not walk:
Mold spores are fungi. Fungi are neither plants nor animals but are a separate kingdom in biological classifications.
Look at the wall below:
That's toxic mold.
Toxic mold exposure can be devastating to your health. To be clear: not all mold is toxic, but the mold displayed above is. That mold type is known as "black mold", and frequently found in the developed world.
Mold primarily originates from water damage - whether that's from a flood, humid air, or leakages. In humid or wet materials, mold has the ultimate means to multiply and spread.
What materials precisely?
Well, wood products, carpets, cardboard, drywall, insulation, paint, ceilings, wallpaper, and even dust are favorite mold growing places.
No, that 10-50% is not a joke--it's a tragedy.
And that 50% estimation may even be low as people with mold intolerance are affected by an even greater percentage of buildings.
So how can mold hurt you?
Of course, mold can also build up in your food, but you'll generally throw away moldy food once it's spoiled. A moldy wall can stay in place for decades while emitting toxins that entire time.
And while these toxins are not living organisms in themselves they can be damaging to you.
Let me tell you:
In the "best case scenario", mold exposure makes you breathe more poorly, irritated, and give you a headache. Simply put, you'll have a small allergic reaction but are fine afterward.
During the worst case scenario your entire immune system shuts down (or goes nuclear), with a disability, being bedridden, seizures, and finally death as possible consequences. Yes, mold really kills people over time - its health consequences are wildly underestimated.
Of course, there's a large continuum of intermediaries between these two extreme responses to mold.
I've lived in moldy buildings before, and I presume I'm one of the "lucky" people who is not immediately affected by mold (to any great extent at least). Working inside a moldy home and sleeping outside during the summer ensured that I could still perform reasonably well.
Not many people are that lucky...
If you're sensitive to mold, just entering a building can trigger your immune system for the rest of the day.
Keep in mind that there's no scientific consensus on toxic mold - some scientists assume that mold poisoning is a pseudo-scientific concept. I'm very skeptical of that claim.
Even established institutions such as the World Health Organization and US Food and Drug Administration consider mycotoxins significant to health in one way or another.
Answer: there's large variability between your individual capacity to handle mold toxins--there's also no current lab test definitively establishing that capacity. Based on the symptoms seen in thousands of individuals, nevertheless, it's safe to conclude that this variability exists.
One problem with combating mold is that a lot of scientific research still needs to be carried before diagnosis and treatment can be simplified.
But let's consider the question: "why is mold such a big problem today?" from another angle. Why didn't people living in Ancient Greece or the Middle ages have mold problems?
Double walls, triple layer glass, less air circulating from outside into buildings, and maximized energy-efficiency all build on that principle.
If mold grows in an airtight buildings you'll be exposed as long as you spend time in that building. The mold thus stays "trapped" while clean air cannot enter.
A 1,000 or 5,000 years ago things were very different...
Primitive societies live in buildings such as huts. These buildings are often not fully airtight. These people additionally only slept inside--they don't spend their entire day indoors.
Remember that modern humans, on the contrary, spend 90% of their days indoors. Individuals living in hunter-gatherer societies only do so for 33%.
Your modern airtight home thus becomes a toxic prison if mold grows there...
Another reason why mold used to be less of a problem is because in nature, the conditions in which mold can continually grow and spread are almost never present. Almost no situations exist wherein mold can grow for years in a specific medium while being fully isolated from the environment.
So you might be thinking: "how does mold affect me in the first place?"
The following analogy can help you imagine the effects:
While eating moldy food your immune response activates just once. Breathing mold, however, can force your immune system to continually activate (if you're sensitive).
So if you're spending up to 16 hours inside a moldy home your immune system is triggered all the time. As a consequence you'll become progressively more fatigued in time.
The consequence is that you can no longer think straight, get tired, dizzy, and that's just the beginning. Again, people end up disabled or even die because they're too weakened to spend any more time in a mold-infested environment...
That's tit, the mold basics you need to know. Next, number eleven - another danger you may know of:
Asbestos is a mineral that can be highly toxic - if the particles become volatile.
The mineral naturally occurs in the soil, especially in rock, and has been mined for most of human history because of its special chemical and engineering properties.
Fortunately, almost everyone knows that asbestos is toxic today.
And even though asbestos' toxicity was officially understood in the 1920s, governments only recommended scaling back its usage 50 years later.[227; 228] The asbestos industry additionally knew about the negative health effects of their products but kept information hidden for a long time.
Many products made in the 1960s to 80s therefore still contained asbestos, such as insulation in walls and around machinery, piping for sanitation, roofing, floor tiles, and even clothing.
As often is the case with toxins, governments act once a problem can no longer be ignored (and when most damage has already been done). Sadly enough, government policy in response to toxicity is usually reactive.
If you're living in a developed country today, your governments is probably extremely thorough in preventing asbestos pollution fortunately - giving credit where credit is due...
If asbestos is spotted in a US school, for example, that building will be inspected every three years to see whether the compound is not emitted into the air (unintentionally).
Asbestos particles thus need to be released into the air in order to become health-damaging.
If you're renovating an older home or you're removing asbestos insulation along water piping, you're at risk for asbestos' negative health effects. Of course, always get professional clean up for asbestos in your home or workplace.
One of the most deceptive dangers of exposing yourself to asbestos is that it can take years before negative health consequences finally show up.
You won't feel anything - initially...
While that's a short list, these health consequences are not fun to experience at all. The list of consequences is somewhat similar to that of radon - with lung cancer as the primarily associated disease.
Don't break the stuff containing asbestos or make it volatile. And if you suspect problems due to asbestos exposure, a CT scan is best to detect lung cancer from asbestos exposure early on.
Just two more air pollutants to cover.
Next up are toxic heavy metals, which are found both indoors as well as outdoors:
First of all, have a sign of relief:
Airborne heavy metals have, fortunately, been declining steadily (in developed societies).
Many heavy metals are toxic in very minute amounts. Lead and cadmium are examples of such heavy metals. While a heavy metal such as arsenic or mercury can also be emitted through the air, I'm restricting myself in order not to over-complicate this post (further).
Keep in mind that heavy metals are not always toxic: you need some heavy metals in your system, such as iron and zinc.
But back to the topic of toxic metals: let's being with lead...
Again, first a positive message:
Lead was added to fuel sources because vehicles run a lot better with it and engine performance goes up. That higher car performance comes at a terrible cost if you're around those cars of sitting inside of them, as you'll then be breathing in that toxic lead.
I have to give a compliment to governments here: airborne lead levels have fallen between 95-98% in the last decades.
Credit where credit is due...
A few problems though:
Some countries such as Algeria and Yemen still add lead to their gasoline.
Additionally, air travel is tragically not yet mandated to use fuel that doesn't have added lead. If you're living closer to an airfield, you're at risk of being exposed to (much) higher lead levels compared to those who don't live close to an airfield...
But why worry about lead in the air in the first place?
Let me tell you:
So how does lead end up in your body in the first place?
Let's find out:
Lead is even stored in your bones.
Please keep in mind that not all lead exposure thus occurs through air pollution from industry or fuel exhaust.
Lead can also be found in many paints. Buying paint that does not contain lead for your home is thus essential. Lead is still used in some workplaces - which is dangerous as well.[253; 254]
Bottom line: avoid lead like the plague...
Even though it's not as well known, cadmium has a similar profile as lead. And just as lead, cadmium is also a heavy metal and can be inhaled through air pollution.[266; 267]
Cadmium can cause organ damage to the liver,[268; 269] kidneys (although some conflicting evidence exists),[270-274] brain and nervous system,[275-277] may promote male and female infertility,[278-279; 282; 286] gives rise to different types of cancer,[287-291; 374; 375] and much more...
(I confess: I'm almost done with these depressing lists...)
Keep in mind that research regarding cadmium is really rudimentary again.
Right now, it cannot be proven beyond a shadow of a doubt that cadmium does not inhibit fertility in humans (yet), even though many animal studies demonstrate that cadmium reduces fertility.
Some institutions insist that more research on cadmium needs to be carried out to definitively establish many of its negative health effects.
And there's (some) truth to that statement...
But I'm already recommending you to reduce your exposure as far as possible anyway. Why? Simple: an extreme number of negative health effects is already observed across the board due to cadmium exposure.[280; 281; 283-285]
I don't need to see 100 more studies on the negative health effects of cadmium - current evidence is already devastating...
Pointing at tobacco as the main culprit can give you a false sense of security though.
As a byproduct of industrial processes, such as the refinement of metals such as zinc, aluminum, or iron, cadmium can be released into the air around factories.[292-295]
Don't just protect your eyes when working on metal. What you breathe matters as well.
If you're living around a cadmium-polluted area, for example, the amount of cadmium in your blood can be significantly higher than in non-polluted areas.
While tobacco smoke is thus most likely to poison you with some cadmium, high levels of cadmium from industry are most dangerous because you can get exposed to a very large dose instantly.
Oh yes, I've got a present for nerds - just to demonstrate how complex the air pollution problem can be:
Yes: while this air pollution type may sound counter-intuitive, space nevertheless has effects on the air quality down on earth.
Solar flares, for example, which are momentary increases in the sun's brightness, don't just entail that more light reaches the earth. Instead, mass is literally emitted from the sun that travels here. That mass emitted by the sun is bombarded on the earth.
Although different in character, energy from space is thus a form of "particulate matter exposure"...
If you're interested, watch the following video on particle matter pollution from space.
Contrary to many's expectations, solar flares and winds can have medical consequences. After an eruption from the sun, people with multiple sclerosis are more prone to have an exacerbation and be admitted to the hospital. Your heart and circadian rhythm also respond to solar eruptions.[515; 517] Incidences of headaches, surprisingly, do not go up.
Of course, energy emitted from space also interacts with the earth's magnetic field, which is another mechanism by which the sun can create a form of particulate pollution. Unfortunately, the research into solar eruptions upon health is really rudimentary now.
That's it: thirteen different types of air pollution.
Please keep in mind that I've not even included all types of air pollution out there. Phthalates, which are contained in many beauty products, are not treated. Other heavy metals that can be polluting as well, such as arsenic or mercury.
Nevertheless, air pollution does have another side-effect that I need to tell you about:
So let's do a quick refresher on sunlight:
Sunlight emits several types of light, such as "infrared" light (part of which gives you heat sensations), "visible" light (consisting of all the colors of the rainbow), and "ultraviolet" light (which can give you a sunburn).
You need ultraviolet light exposure on your eyes to create more "dopamine". Dopamine is a brain signaling substance that gives you motivation and well-being, while making you more assertive.
Ultraviolet exposure to your skin is also essential to help you feel good and to produce vitamin D.
One study - unfortunately published in Chinese - demonstrates that high air pollution levels lower ultraviolet light exposure from the sun up to 50%.
That 50% reduction is insane.
Let's explore some examples that make you familiar with the effects of such a reduction:
If I'd be exposed to sunlight in the mid-summer in the Netherlands under heavy air pollution, ultraviolet light levels are reduced to mid-spring or early-fall levels.
Say goodbye summer...
If I'm in southern Spain for a summer holiday and there's heavy smog there, the sun's strength would be equal that of southern Norway's level.
For nerds: southern Spain's UV index of 10 would be reduced to 5 (the estimated maximum at Oslo, Norway).
Keep in mind that the examples above signify extreme air pollutant levels. Nevertheless, you can always expect an effect of "sun blockade" if particulate matter or ozone are present...
Still think city life is optimal?
Much worse than "winter is coming":
winter is staying forever.
Getting your daily sunlight in polluted environments is thus not optimal.
(Nerd section: of course, the pollutants described above also interact, and their negative effects accumulate if you're exposed to a higher number of pollutants. Higher dosages are also more damaging...
Oh by the way, congratulations.
You've now completely read trough the depressing list of air pollution health effects. The next step is to look at measuring these effects in your unique circumstances and finding solutions.
The topic of air pollution measurements is treated first...
In this section I'll tell you why measuring air quality is necessary - at least, if you want to control and minimize the air pollution you're exposed to.
Remember that I laid out thirteen different air pollutant categories in the previous section. Measuring all these pollutants would be very time-consuming.
Don't worry though: you don't have to measure every air pollutant in your environment.
I'll tell you why soon...
Air quality is measured 24-7 in most of the developed world. That real-time data allows you can estimate the air quality in your environment.
Estimate is the key word there though...
(For nerds: besides local measurements of emissions, satellites, and air transport models of pollutants add additional predictive power to such measurements.)
That air quality index bright side is that many outdoor air pollutants I consider most important are taken into account in that index:
The bad news?
Not every station around the world is equipped to measure all pollutants. Only PM2.5 or PM10 are measured routinely, for example.
Let me tell you why...
You cannot exclusively rely on the air quality index that's measured close to your working or living place.
The air quality map I've posted above only give you a general impression of what to expect in your living and working area. A general impression is just that: a general impression or estimate.
Why my recommendation?
(Even though I've made the same argument in my guide about particulate matter, I'll include it here for completion sake.)
Don't believe me?
Look at the maps of different cities below. First London:
Observe that in the city center there's more than a 2-fold difference between the 23 and 56 readings, even though these readings are made a few blocks apart.
Then there's Bangkok:
Again, the difference between 53 and 129 is more than 2-fold within a two block distance. Then, lastly, there's Sao Paolo:
In this case, just one street makes the difference between a 34 and 59 reading.
All of these readings, moreover, also change quickly when the wind turns direction or wind speeds ramp up or slow down.
Sunlight that suddenly reaches the earth's surface (when clouds dissipate) create lots of ozone in an instant, changes in traffic may create new pollutant patterns (particulate matter, nitrogen dioxide, carbon monoxide), and industry that turns on affect almost all readings instantly in a given place.
Air quality is thus a decentralized and local phenomenon.
A 28 - 59 air quality reading in Sao Paolo on the map above thus only tells you that overall air quality is good to average.
And if you look at Bangkok, you observe that no area is really safe.
For a budget option, click the following picture:
PM2.5 is one of the most important air pollutants out there.
For a higher-quality option click the following picture:
That higher-quality air quality monitor measures particulate matter (PM2.5 and PM10), two VOC indications (formaldehyde and total VOCs), temperature, and humidity.
In most cases, higher particulate matter levels are associated with higher nitrogen dioxide, sulfur dioxide and ozone levels, and vice versa.
Most of these air pollutants have the same sources, such as industry, energy production, and fossil fuels used in transportation.
Of course, if you do want maximum certainty, by all means buy testing equipment for nitrogen dioxide, sulfur dioxide, and ozone.
More testing is always better, although I'm not describing how to do so in this guide. I'm just supplying you with an account that works for most people.
You're probably part of "most people", and this guide will this help you.
If you're living near industry where metal is smelted you could consider testing for cadmium. Battery production, mining, waste incineration other types of metalwork are other instances in which cadmium testing is advised.
You can buy a heavy metal test (to test blood levels) here.
Dictum: know thy environment (as opposed to "know thyself").
Let's find out...
Remember that the main indoor air pollutants (covered in this guide) are:
Let's go over these options one by one.
Homes, school, and workplaces can be tested with such a kit. If you want to test (many) different locations, I'd recommend buying an electronic radon detector.
The best solution to carbon monoxide poisoning (or even breathing the substance without symptoms appearing) is to use carbon monoxide meters near critical places such as central heating systems.[52; 53]
Click the image below to find a carbon monoxide meter:
Measuring carbon monoxide output at critical locations prevents most of the damage from occurring in the first place. Remember that low exposure levels, once they becomes high enough, are damaging.
You may think: "but what I you do get poisoned?"
Accurately knowing whether you're poisoned by CO is not so simple.[25-27; 61]
Analyzing carbon monoxide in your breath can only yields information about your short-term exposure levels. Regular oxygen saturation tests are also useless for spotting poisoning.
A blood test is a better solution. But if you get above a certain threshold on that lab test, you'll only know that you've been previously exposed to carbon monoxide--you don't know for how long you're exposed or what the expected development will be...
The most important solution is to remove yourself from the situation and use oxygen therapy (at the hospital). Of course, also remove the source of CO poisoning (in your home)
Additionally, there's CO's cousin:
You may think: " Sure, you can measure carbon dioxide levels but is that really necessary?"
Carbon dioxide detectors are not cheap, unfortunately, as they're not as widely used as carbon monoxide meters.
(You can buy a carbon dioxide detector HERE.)
But why measure your carbon dioxide levels in the first place?
CO2 levels give you an indication when you should open up your windows. Many people have no clue how high their indoor carbon dioxide levels get without actual measurement.
Gut feelings are not good enough...
Remember: you can increase brain performance and well-being by simply making sure enough clean air enters the building you're in. Taking care of CO2 in your indoor environment is one of the simplest air quality actions you can take...
Visual cues are the best way of finding out whether buildings are water damaged.
Beware of false negatives when going off visual cues though: if you see water damage or mold, it's safe to assume that the environment is toxic. If you don't see water damage or mold, however, you cannot definitively conclude that you're 100% safe.
Mold diagnosis is highly complex.
Click HERE for a methodology that can be used to rule mold toxicity out (or in).
Answer this question: can it reasonably be expected that asbestos is present in your building?
To answer that question you need to know that buildings constructed before the 1990s are prone to contain asbestos.
Always make sure to inspect older buildings.
The most important sign to look for is the degradation of building materials. Walls, pads on stoves, piping encasement, insulation, vinyl floors, may all have cracks or falling apart. Signs of dust near building material is also problematic.
If building materials are degrading then make sure to test for asbestos.
Never (further) disturb asbestos until it's safely removed from the building.
All basic air pollutant measurements you need to know about.
The good news:
Time to enter the kingdom of heaven.
Well, even in the city you can reduce your air pollutant exposure levels up to 90%.
Let's find out how...
I know what you're thinking:
"That list of 13 pollutants was overwhelming."
"There's no safe place on this planet unless I move to the North Pole"
"Air pollution is everywhere in my city so there's nothing I can do"
I know that feeling...
But there's no need to stress.
Don't get bogged down by the sheer amount of info: if you just implement two solutions instead of none, you'll still have enormous benefits...
I'll also tell you which strategy lowers which specific air pollutant.
Ready for one last tour de force?
"Abandon all fear, those who enter here..".
Here we go:
(Reduces exposure to carbon monoxide (CO), carbon dioxide (CO2), radon, and any pollutant associated with cooking or heating)
Yes, sometimes solutions are very simple...
This tip might sound like common sense, but ventilation is absolutely necessary to reduce toxic buildup over time.
Hopefully you've got a view like this when opening your windows...
Just opening your windows a few times a day, for a short period of time, allows these gases to leave the building.
Without opening windows, indoor CO2 levels start to approximate dangerous levels such as 2,000 - 5,000 parts per million over time.
Opening windows thus brings those levels 75 - 90% down.
If you're spending time in buildings next to the highway or airport, opening up your windows will bring many new air pollutants inside (e.g., particulate matter, carbon monoxide, ozone, nitrogen dioxide).
So how should you deal with that situation?
There's a simple rule:
Get a CO2 detector and keep windows open long enough for its levels to come down. If CO2 levels go down radon exposure also goes down.
Once CO2 levels are low again, close your windows so that fewer outdoor air pollutants enter inside.With low CO2 levels you can also reasonably expect that oxygen levels are high again.
An additional situation also exists in which opening windows is highly recommended:
Let's say you're using products that contain lots of VOCs, such as paint, household or "cleaning" products, or preservatives for wood. If you're painting the walls inside your house and you're keeping the windows closed, VOC levels can increase 1,000-fold.
Yes, that 1,000 fold is not a typo.
Using household products that contain VOCs can also increase indoor pollutant levels dramatically. In those cases, it's smarter to temporarily open up your windows to let air pollutants leave your home.
Remember: most of the yearly air pollution deaths occur because of indoor air pollution.
Using a wood stove or fireplace is especially dangerous.
EPA-certified stoves and fireplaces emit 80-90% lower air pollutants. Additionally, always turn on your range hood when cooking and make sure you've got a chimney for your stove in the first place.
Not only the air pollutants are dangerous here, the charring is so as well.
Wood stoves should always be well-maintained as they lose efficiency over time. More pollutants will escape if stoves are not kept airtight. You should be especially careful with burning plastic or waste products - doing so creates extremely toxic pollutants.
If pollutants originate through indoor heating systems they also need to be removed from buildings properly. Of course, opening up windows counteracts the goal of indoor heating-- it's thus important to strike a good balance.
You may think: "who burns wood anyway nowadays?"
2 million people are killed on a worldwide basis every year due to indoor cooking with open fires.
"Modern" gas cooking stoves can be dangerous as well, although some contradictory evidence exists.[390-392] Gas stoves are still widely used in the developed world--again: make sure to use a range hood.
And how about indoor mold? Opening windows won't work--I'll return to that topic soon.
Bottom line: proper indoor ventilation can prevent many indoor air pollutants from building up
And you've got lucky:
The second strategy is just as simple as the first one...
(Reduces exposure to all air outdoor pollutants, depending on circumstance, including nitrogen dioxide, PM0.1 and PM2.5, and carbon monoxide)
If you want to avoid air pollution, you should avoid getting near the smoke emitted from a campfire right?
The same principle applies when you want to avoid air pollution in cities:
Yes, it's that simple...
Here are some guidelines:[104; 376-383; 430; 431]
"You're not exercising in nature, human?! That's crazy!"
But what if you've got lots of air pollution indoors precisely because you're living in a big city?
In that case:
(Reduces exposure to almost all air pollutants except a few gases)
In my previous blog post on particulate matter's disastrous health effects and strategies to reduce its damaging effects, I've integrated seven existing air purifier reviews. I.e., the outcomes of seven high-quality air purifier reviews were combined into one new review.
With that method I'm ensuring you're getting the highest quality product at the lowest price.
I'll use the results of that review's outcome in this blog post as well.
I'll cover the basics of my previous recommendations here--if you want to read the full details, consider the HEPA air purifier section in my particulate matter blog post.
Let's first consider what kind of air purifiers I've included in my recommendations:
These filters have different purposes. True HEPA filters are targeted towards particles and can capture up to 99,97% of particulate matter (when the filters are working properly). Carbon filters, on the other hand, filter out (most) gases (such as VOCs)
(Prices listed below as per 4 November 2018.)
But let's say 300+ square feet filtering air purifiers are not good enough for you.
You may even want to filter an entire apartment with one air purifier...
In that case:
The best air purifiers that exist out there. Again, for a full review and my complete methodology read the air purifier review section of my particulate matter blog post. That section also contains many scientific references telling you why I think air purifiers are a great solution.
Oh, one more thing:
If you're located in a smaller city or in buildings outside the city, the question of whether to use purification depends on how bad the air pollution is. In that case, again, you'll need to measure...
It's your call...
Your home? No need for an air purifier unless you're smoking inside or using a polluting wood stove.
That's it again...
So what's next?
I'll now tell you how to reduce your allergen, dust (mite), and particulate matter pollution even further:
(Reduces exposure to dust mites, allergens, smaller particles (PM2.5 and PM0.1)
Just like there's a quality difference between regular air filters and HEPA air filters, there's also a difference between regular vacuum cleaners and HEPA vacuum cleaners.
Let me explain why a HEPA vacuum cleaner may yield indoor air quality benefits:
Some particles stay in the air for longer periods of time, such as smaller particulate matter (PM2.5 and PM0.1) or pet dander. These smaller types of pollutants are best cleaned with a HEPA vacuum cleaner.
If you've got allergies, or a lung or heart disease, a HEPA vacuum cleaners also become more important (to maximally lower your particulate matter exposure). And if you're cleaning a home or office because it has leaded paint, then a HEPA vacuum cleaner is highly recommended as well(combined with respirators, which are treated later on).
Don't waste your money...
Being more precise:
Some particles quickly settle on the floor, such as dust (and their resulting dust mites). For those types of pollutants you just need regular vacuum cleaner.
Vacuuming is one of the most important methods to reduce dust mite numbers.
(Unfortunately, casings on pillows and mattresses are proven not to work conclusively in preventing dust mites.)
If gases or heavier particles (PM10+) are your main indoor pollution problem, you don't need a HEPA vacuum cleaner either.
Again, please realize there's no universal solution for dealing with air pollution...
(Remember that most particulate matter is emitted in cities (transportation), industry, or through polluting types of energy production - that stuff is everywhere)
In terms of HEPA-vacuum cleaners, you've got two options:
Just as with using an air purifier with HEPA filter, using a HEPA vacuum cleaner correctly is paramount. If you don't replace filters over time, efficiency will go down.
(Reduces exposure to all outdoor air pollutants such as particulate matter and different gases (ozone, carbon monoxide, sulfur dioxide, nitrogen dioxide)
Remember I told you that buildings in the develop world are insulated so that they have low levels of ventilation nowadays.
So you may say: "wait a second, don't allergies generally increase with poorer building ventilation systems?"
"And now you're recommending insulation, which decreases ventilation...?"
So why do I recommend to decrease ventilation (in some instances)?
I'll tell you in a second...
Let me first sketch a background:
In the developing world, buildings often have better ventilation, but through indoor cooking lots of pollutants are emitted - it's not just ventilation that matters...
You see, ventilation can help you or work against you.
If you're living in a metropolis, increasing ventilation entails that more air pollutants enter the interior of your home all the time - which is a bad deal.
It's probable that no no extreme insulation is needed
against outdoor air pollution protection in this case...
Let's consider why insulation works:
On average, closing all windows alone can reduce air exchange by 50%. Making all windows and doors airtight will lower air exchange much further - my guesstimate is upward of 90%.
Spending time in an insulated building at peak pollution times dramatically lowers your exposure to pollutants. Of course, if your indoor environment is tremendously polluted as well, then staying indoors to avoid outdoor air pollution won't be of much help.
If lots of indoor air pollutants in the form of VOCs are emitted from your furniture, you may also be worse off being insulated. Burning incense, using detergent, or stir-frying, for example, can already have small but noticeable effects on your health, .
The best solution combines insulation, moving indoors and using a high-quality air purifier (which was the third strategy mentioned above) at strategic moments. Remember: to know when you should move inside you need to measure air quality...
And while it's common sense the following advice bears repeating: avoid smoking inside the house. Smoking is one of the worst ways to pollute your indoor environment. Of course, other people's health will also be negatively affected if you smoke indoors.
Higher humidity levels, due to improper insulation, increases the chances of mold buildup - a topic I'll get back to soon.
Of course, improving insulation on an existing home takes time and money - which is the downside of this strategy.
While it's not a quick solution, it's nevertheless a strategy you should consider if you live in a polluted environment and don't want to move. Proper insulation of buildings is a necessity in air polluted environments, as without insulation you're exposed to that pollution 24-7.
The following strategy also (often) has to do with insulation:
(Reduces exposure to radon)
Remember radon, the radioactive substance entering buildings from the soil?
Fortunately, you can always control how much radon enters buildings.
Keep in mind that having a newer building type does not exclude you from testing radon levels. The structural integrity of the building is what fundamentally matters, as well as whether radon levels are high around the building in the first place.
Homes are the most common source of radon exposure.
The first action to take is to test indoor radon levels. If radon levels are elevated you can take action for reducing them.
Testing for radon exposure can be really inexpensive. Again, you can buy a radon testing kit for basic testing. If you want to investigate many environments for their radon levels, however, buy an electronic radon detector.
A problem with testing for radon is that levels vary throughout the year, with seasons, and by changing weather. Radon is thus ideally tested for longer periods of time to get a complete picture of your exposure levels.
You've got several options if high radon levels are detected: a building might need an anti-radon barrier in the basement, increased ventilation under the floor or on ground level, better insulation between the basement to the main floor, etcetera.
Most of these alterations entail making changes to the construction of the building. Bringing in a radon expert can help you with this problem.
Again, 100% of buildings can be fixed for radon exposure. The quintessential problems are that radon levels are not universally measured or that problems are not proactively solved.
Just measure and take action.
The following strategy is simple again, and yet, not universally applied:
(Reduces the negative effects of all air pollutants)
If you're eating at MacDonald's and Burger King twice a day, air pollutants are simply going to hit your health harder.
Let's go through these foods and nutrients one by one:
Couunter-intuitive air pollution harm-reduction strategy...
Don't get too bogged down on the specific food recommendations above though: many food sources high in antioxidants such as dark chocolate or berries have not been studied yet.
I do expect that many other healthy foods, which may not be listed above, still help you reduce the negative health effects of air pollution.
Your favorite oysters, spices, and spinach probably all contribute...
On another note:
The more ozone you're exposed to, for example, the more vitamin C and E are depleted in your skin. The skin itself may also age faster when exposed to particulate matter.
Eating a nutrient-rich diet thus becomes more and more important with greater air pollution levels...
Next, an indoor air tip:
(Reduces exposure to VOCs, heavy metals)
Yes: your furniture is likely polluting your indoor air.
New furniture very often emits formaldehyde, an example of a VOC. Household and cleaning products, drapes, cushions, laminate flooring, varnishes, and scented products also commonly emit VOCs.[477-481] Even printers and copying machines emit VOCs.
Because thousands of different VOCs exist, I'm not going to consider them all individually.
I just have this recommendation instead:
A hardwood or stone floor is better than laminate, for example. Cushions from organic wool or cotton are better than cushions with a coating.
I know furniture and indoor products that do not emit any VOCs are much more expensive so the goal here is to slowly transition to more natural products.
One strategy to get more natural products is to live smaller: perhaps you don't need a gigantic house and can opt for a smaller house while affording more natural in-home materials.
Just look around, natural alternative are almost always available...
And keep this principle in mind:
It's thus recommended to remove packaging from furniture outside so that VOCs are not released in your home. You can even leave furniture outside for a while so that the most damaging gases are gone.
Make sure to store any products that emit lots of VOCs - such as regular paint - sealed and removed from your living areas.
And let's move to another paint-related topic:
Selling paint with lead has been forbidden since 1978. Nevertheless, realize that that exposure to leaded paint is possible: if you're considering buying a home that's built before 1978, I'd be very wary of the paint there.
Let professionals remove that leaded paint first.
Conclusion: unnatural in-house materials will give your home unnatural air - avoid like the plague.
The following air quality tip is indoor quality-related as well:
(Reduces exposure to mold)
Remember mold toxins?
These toxins are produced by fungi and are dangerous if emitted by damp walls or bathrooms that remain wet.
And you know what?
In such cases you might need to fully remove yourself from the toxic situation, leaving (almost all) your belongings behind.
The problem is that most possessions inside a building are almost certainly contaminated if mold is found there.
Material such as paperwork or pieces of clothing, insofar they are porous to water, are usually lost forever when infested. Even washing belongings will not always remove all the mold toxins as washing machines can re-introduce mold into clothing or bedding.
If you do bring material with you, make sure that material is stored airtight so that no potential mold can be released.
Only some possessions can be de-contaminated from mold over time - these belongings are often made of "inert" materials such as glass or metal.
In that case you'll have to live in a mold-free environment for some time.
If you're mold sensitive, a few weeks outside a toxic environment is often sufficient to realize your environment was damaging. Beware: removing yourself from the toxic environment can make your symptoms worse initially.
If you do get re-introduced to mold after a mold-free period, your symptoms will generally be more extreme. The upside is that such re-introductions solidify your understanding that mold is truly the culprit and that mold-illness is not "all in your head".
Staying in hotels or having a tent in your backyard is often not radical enough of a solution if you're really mold-sensitive.
Yes: mold issues can be that extreme...
To determine whether a location is "safe" for you to spend time in long-term, it's best to live in that location for a couple of weeks, but if and only if you've been fully symptom-free previously.
A great way to test for mold susceptibility -
if you've got the cash for an RV. I certainly don't (yet)...
If you're really susceptible to mold's negative health effects you might need to avoid (strong) mold pollution for the rest of your life - in the most extreme case scenarios.
Many people who have successfully removed all mold from their lives still get extreme reactions to minute quantities of mold if they're re-exposed.
Let me explain:
Such reactivity is a sign of poorer overall health, but fortunately, that reactivity may improve in time.
Overall, if you suspect mold toxicity, it's better to be safe than sorry at first...
Years of your life can be spent being negatively affected by mold if you don't act proactively. Again, mold grows in insulation or drywall, and is not always visible to the naked eye.
Without testing you'll never know for sure whether your health issues are caused by mold.
On another note:
There's (anecdotal) evidence that the combination of electromagnetic frequencies in the environment (WiFi, cell towers, smart devices) makes mold much more aggressive. Placing a WiFi router in a mold infested cabinet may thus create exponentially more toxins.
Still want to undo mold damage?
In that case it's best to get a qualified mold inspector (and cleaner) to investigate your house or office to make sure it's fully cleaned. DIY bleach, vinegar, or other store-bought products do not solve the problem completely and may make issues worse long-term.
Keep in mind that I'm doing no justice at all to the complexity of avoiding and treating mold issues here. Exhaustively treating the basics of mold probably needs a 500 or 1,000-page book.
I'll probably be writing a full blog post on this topic in the future.
For now, I'd strongly recommend you visit the "mold avoiders" Facebook group if you're suspecting any issues mold-related in your life. That group has tons of free information that help you overcome mold problems.
Successfully dealing with mold takes building up lots of experience. As a mold-sensitive person, you'll slowly learn what types of exposures trigger you and which don't. Mold toxicity is not a problem which you can usually beat in a week...
Let's now consider a simpler strategy:
(Reduces exposure to dust mites, toxic mold, VOCs)
Both very high and very low humidity levels are not optimal for your health.[462; 463] I'm talking about "relative humidity" here, which is water vapor measured as a percentage of the total amount of vapor in an area.
Controlling indoor humidity levels is a great way to reduce indoor air pollution...
And by lowering humidity to 0 - 35% for just a couple of hours a day you can reduce dust mite numbers up to 95%. Additionally, a longer-term 50% humidity level is great for countering dust mites buildup.
Lower indoor temperatures - such as 18-20 degrees Celsius - are also protective against dust mites compared to higher temperatures (such as 21 degrees).
Very long soaks of clothing and bedding in warm water with laundry detergent and bleach can also kill dust mites, but that "solution" will expose you to more VOC chemicals.
More good news:
Fungi grow best if humidity levels reach 60%. Building materials also damage more easily with higher humidity levels. Paint may peal with high humidity, for example, and moisture is more prone to build up between walls.
That moisture feeds mold buildup in turn.
In general, avoid exceeding the 60% humidity level. Optimal humidity levels can have big health benefits - you'll improve work performance and may even improve sleep quality.
To reach that 50% level, you would need some air humidification during the wintertime in colder climates. Steam humidifiers are the best - they do not emit pathogens into the air.
The problems with remaining high humidity levels during the wintertime, however, is that windows can start freezing - you'll need to strike a good balance.
But let's consider the opposite end of the spectrum:
With humidity levels under 40% people begin to show those symptoms. Bacteria and viruses also spread more easily at lower humidity levels.
Keep in mind that I'm only giving guidelines:
The effects of different humidity conditions are extremely complex. In the wintertime, low humidity increases the amount of particulate matter in the air, for example. During the summertime, the opposite happens.
Each pollutant is individually affected by humidity levels...
But let's consider some red flags in relation to controlling indoor humidity:
Having a basement that has lots of water, pipes that leak, or a damaged roof may all contribute to humidity problems inside the house. (Central) heating systems can also be sources of higher humidity levels.
Simply put, structural damage to any building is dangerous as humidity levels can easily get out of control - an issue I considered with mold earlier.
Additional solutions to lower humidity levels are ventilating buildings, avoiding hot showers, , using your kitchen exhaust, removing rugs, and ventilating rooms where washing machines or dryers are placed. For the worst-case scenarios, use a dehumidifier.
So what's next?
I'll now help you prevent air pollution from showing up at your doorstep in the first place.
Let's summon the forest gods (or vegetation in plain English)!
(Reduces exposure to all types of outdoor air pollution)
No shit Sherlock!
This strategy is extremely simple:
The more plants around your residence or workplace, the lower exposure levels to air pollutants will be. Depending on what study you look at, the effects of vegetation are either really minor or extremely large.
In some instances vegetation can increase the level of air pollutants though.
Vegetation, and trees more specifically, reduce ventilation. Planting lots of trees next to a road will entrap some of the air pollution emitted by cars, increasing air pollution levels at that road while reducing air pollution in adjacent areas.
That principle should teach you an important lesson:
Pines and conifers are especially effective. Even green roofs will help reduce air pollution levels.
The levels of some of the worst outdoor air pollutants types, such as ozone (O3), particulate matter (PM) and nitrogen dioxide (NO2), can be reduced dramatically. Heavy metals such as lead or cadmium can be captured by these plants as well.
That's great news...
Up to a whopping 90 kilograms of PM10 and 35 kilograms of PM2.5 per year alone by covering more than 90% of the roof by Pinus mugo var. pumilio (Dwarf Mountain Pine).
Other good pine options are:
Additionally recommended plants are:
The Japanese Maples have been tested as excellent reducers of ozone (O3). Magnolias are great for NO2 reduction.
Why plants such as pines?
Blue dwarf pines: excellent particulate matter
Some regular ground-level plants such as Spiraea japonica (Japanese meadowsweet) and Philadelphus pekinesis are also helpful. These plants have only been tested in Chinese studies though...
The difference in how well different plant species capture air pollution varies many-fold, so it's essential to buy the right types...
Keep in mind that rain or wind will lower the amount of air pollution that's captured by vegetation. I do not see great methods to reduce plant's exposure to rain or wind (yet), however.
Simple pine trees: building a wall of them around your house is
one of the best air purifiers out there.
But let's further simplify my message:
Evergreen plants are also better than plants that leave their leaves during the wintertime. Fortunately, pines are evergreens.
Indoor plants have been proven to lower the amount of VOCs and ozone, for example.[482; 484; 485; 489] Make sure to treat your indoor plants well: giving plants more light will increase their filter-ability.
The following plant species have been tested to reduce VOC levels:
Spider plants, moreover, seem to be specifically effective in removing particulate matter from the air.
Bonus: indoor plants also reduce CO2 levels.
More light for plants also improves their CO2 reduction. Consequence? An indoor air quality improvement due to plants translates to fewer symptoms if you have lung disease.
And in case you're wondering: no, I don't remember all these Latin names from memory--but these names may nevertheless help you get the right plants into your home when you ask the gardener.
You may have one question left:
I think you should...
In fact, you don't have much of a choice if you're living in a big city: using more vegetation is one of the only ways to save yourself.
In the next strategy, you'll learn how to combat outdoor air pollution if you have to be in a disastrous environment anyway:
(Reduces exposure to particulate matter, mold, common allergens from pets or plants)
I know: wearing a respirator is going to look strange (especially in developed countries):
In Asia, however, wearing respirators is more socially accepted, especially during periods of extreme pollution with lots of smog.
Protecting yourself is highly recommended if you're working with a lawn mower, you're sawing wood, or using a leaf blower.
Nevertheless, a respirator can cut particulate matter exposure by up to 95% - a huge effect. Unfortunately, respirators don't filter out gases such as VOCs or ozone, so avoiding spending time in polluted areas is always your best option...
What if you do wear a respirator though?
Just those two effects alone signify that wearing a respirator has a -stress-lowering effect.
The reason government and health institutions don't widely recommend wearing respirators is that they want to wait for more higher-quality studies that definitively show that heart and lung conditions can be prevented by wearing them.
For me, instant blood pressure and stress reductions are more than enough.[506; 507]
One thing: keep in mind that wearing a respirator makes breathing more difficult.
But let's first take your pollutant-protection one step further:
(Reduces consequence of all the negative health effects of air pollution)
I already hear the excuses coming: "I'm going to skip my sprints today and stay inside - the air pollution is too extreme today".
"No need to take my bike, the air quality index is bad today"
That's a recipe for disaster...
Air pollution is not an excuse to avoid exercise. In fact, the better your physical shape, the more protected you will be against the negative effects of air pollution.
When to exercise?
Ozone levels usually peak in the evenings because of the effect of sunlight. Other air pollutant levels - such as nitrogen dioxide and particulate matter, drop off during the nighttime.
There's another reason why you should exercise anyway, even in polluted air:
The benefits of exercise still outweigh the downsides of air pollution for most people, even in air-polluted areas.[427-429] Wear a respirator, if necessary, and avoid toxic environments when doing so...
Only if you've got severe lung or heart issues or in poor general health would I recommend to exercise exclusively at non-air-polluted locations:
The perfect place to exercise: even if you have lung problems...
Bottom line: move your body...
Just two more solutions to go:
Reading all the above solutions would almost gives you the impression that you should never ever breathe in anything else than 21% oxygen and some CO2.
Nothing could be further from the truth.
Complete sterility is probably devastating to your health.
From the first moment of birth, getting exposed to bacteria is essential. With a vaginal birth as opposed to a C-section, you'll get exposed to bacteria from the vaginal fluid, for example.[454; 455]
Drinking raw milk may also be protective against allergies. If you've exposed to a lower number of pathogens causing infections may also have an increased risk of developing hay fever and other allergies.
And yet, exposure to certain germs such as those found in raw milk is lower than ever today.[456; 457]
Unfortunately, the research into optimal exposure levels and patterns to germs such as bacteria and viruses is still in its infancy today. Nevertheless, overly clean environments are almost certainly not conducive to your health.
So let's zoom out and look at the difference between germs and modern pollutants:
In modern society you're exposed to much more ozone, nitrogen dioxide, and mold than our ancestors were ever exposed to.
More household cleaning product usage also causes more respiratory problems such as asthma. For every year you're living in a developed nation such as Australia, your asthma risk goes up.
The bottom lone is this:
If you do create a sterile environment in your home or workplace that's completely free of air pollutants, you'll probably need to compensate by getting natural exposure levels up. You'll want to breathe in air that's found in forests and other (relatively) clean natural environments.
You cannot spend 24-7 in an environment that contains air purifiers...
Let's explore that concept of sterility a little further:
With the onset of human civilization roughly 10,000 years ago, our relationship to viruses and bacteria changed forever.
Let me explain:
When you begin to stay in one place practicing agriculture, that environment becomes more conducive to spreading certain germs. Increasing population densities also change the dynamic of spreading germs even further - high population densities become hotbeds for some types of germs.[458; 459]
In modern society, you're thus exposed to many pollutants that are completely unnatural from an evolutionary perspective, such as lots of fine particle matter PM0.1, ozone (O3), and nitrogen dioxide (NO2).
You're also exposed to different germs than your ancestors 100,000 years ago and you almost never breathe the air that's found in locations that are unaffected by human action - such as Northern Canada or Scandinavia.
Air pollution is thus a complex problem. I highly recommend spending at least a few hours a week in nature, to make sure you're breathing air that's ancestrally normal.
Play with your kids in the sand...
Both an underexposure to substances that can be helpful in the long-run, and an overexposure to harmful substances can also explain the wave of allergies and lung problems that's plaguing developed countries.
Of course, the overexposure part of the equation is precisely the main topic of this blog post. I nevertheless assume that overexposure and underexposure go hand-in-hand here...
One last strategy:
This strategy is simple but has to be mentioned...
Remember: if you're young, old, have existing lung or heart problems, then you're especially susceptible to the negative health effects of air pollution. The fetus is very susceptible to air pollution's effects as well.[434-439]
If you've got asthma, for example, you have to be especially careful when exercising outdoors in polluted environments - and be more careful with indoor pollution.
The more susceptible you are to the effects of air pollution, the more action you need to take to reduce air pollution's effects on your health.
Of course, moving should (almost) never be your first option...
Nevertheless, if you've got severe lung or heart problems and living in an extremely polluted city in Asia, I'd seriously consider moving to a less polluted environment when you've got cash...
There are other cases as well:
If you're a professional athlete or high-performer then you might want to avoid spending two weeks in a metropolitan city - even if your health can easily handle it...
Let's consider why:
Polluting your lungs can be the difference between reaching the first place or second place on a 400-meter sprint. You don't want to spend two weeks in a polluted place if performance is your goal...
Should you not worry about air pollution at all in that case?
Not at all: air pollution will always do some damage to your health, independent of circumstance.
Less is more with air pollution.
So let's conclude:
After reading all of these solutions, I caution you against being optimistic about air pollution.
Don't assume the problem is going to take care of itself. My introduction of this blog post tells you why:
After air pollutants are identified, governments and institutions take decades to remove them from your environment. The health damage these air pollutants do affects your health right now.
Sure, some bright spots exist.
In developed countries the emission of several types of air pollutants have been declining over the years. Ozone, lead, or particulate matter emissions come to mind.
But don't get too comfortable though:
If you're already susceptible to heart disease, just spending time in a car, the inner city, or near a factory already massively increases your risk for a heart attack.
Also remember that 20,000 people in the UK die every year because of nitrogen dioxide. And 8% of diabetics in Germany, which are a jaw-dropping 500,000 people, have the disease because of that same air pollutant.
Let's put those numbers into context:
If a dictator would kill 20,000 people in Europe, everyone would be protesting the street tomorrow--no, tonight...
But air pollution?
Nothing seen, nothing heard...
And I get it...
You may have become somewhat depressed when understanding all the negative health consequences air pollution can have.
You don't have to feel down though:
Fifteen solutions are enough to save yourself.
Maybe not today, maybe not tomorrow, but in a year you can implement many of them and dramatically cut your risk for disease.
Do the world a favor:
Save yourself first...
And if you save yourself, you can save other people during the rest of your life as well.
Spread the news. You'll make the world a better just one action at the time. Making the world a better place does not have to cost any money.
A few words can change a lot of hearts. I hope my words do - and yours can do so as well. Become your own hero, and become a hero for others in turn...
The world needs you.
Spread the message, and help people save themselves...
*Post can contain affiliate links. Read my affiliate, medical, and privacy disclosure for more information.
Author: Bart Wolbers. Bart finished degrees in Physical Therapy, Philosophy (BA and MA), Philosophy of Science and Technology (MSc - Cum Laude), and Clinical Health Science (MSc).
 World Health Organization International. Air Pollution.
 Climate And Clean Air Coalition.
 BreatheLife Initiative 2030. A Global Campaign For Clean Air.
 Our World In Data. Air Pollution.
 Schlute P, Alegret L, ... Willumsen PS. The Chicxulub Asteroid Impact and Mass Extinction at the Cretaceous-Paleogene Boundary. Science Vol 327 2010.
 Longrich NR, Tokaryk T, Field DJ. Mass extinction of birds at the Cretaceous-Paleogene (K-Pg) boundary. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15253-7. doi: 10.1073/pnas.1110395108.
 Pope KO, D'Hondt SL, Marshall CR. Meteorite impact and the mass extinction of species at the Cretaceous/Tertiary boundary. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11028-9.
 Kaiho K, Oshima N. Site of asteroid impact changed the history of life on Earth: the low probability of mass extinction. Sci Rep. 2017 Nov 9;7(1):14855. doi: 10.1038/s41598-017-14199-x.
 Gowlett JA. The discovery of fire by humans: a long and convoluted process. Philos Trans R Soc Lond B Biol Sci. 2016 Jun 5;371(1696). pii: 20150164. doi: 10.1098/rstb.2015.0164.
 Cornélio AM, de Bittencourt-Navarrete RE, ... Costa MR. Human Brain Expansion during Evolution Is Independent of Fire Control and Cooking. Front Neurosci. 2016 Apr 25;10:167. doi: 10.3389/fnins.2016.00167. eCollection 2016.
 Roebroeks W, Villa P. On the earliest evidence for habitual use of fire in Europe. Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5209-14. doi: 10.1073/pnas.1018116108. Epub 2011 Mar 14.
 MacDonald K. The use of fire and human distribution. Temperature (Austin). 2017 Jan 24;4(2):153-165. doi: 10.1080/23328940.2017.1284637. eCollection 2017.
 Sundell J. On the history of indoor air quality and health. Indoor Air. 2004;14 Suppl 7:51-8.
 Diffey BL. An overview analysis of the time people spend outdoors. Br J Dermatol. 2011 Apr;164(4):848-54. doi: 10.1111/j.1365-2133.2010.10165.x.
 Cincinelli A, Martellini T. Indoor Air Quality and Health. Int J Environ Res Public Health. 2017 Oct 25;14(11). pii: E1286. doi: 10.3390/ijerph14111286.
 Black J. Intussusception and the great smog of London, December 1952. Arch Dis Child. 2003 Dec;88(12):1040-2.
 Bell ML, Davis DL, Fletcher T. A retrospective assessment of mortality from the London smog episode of 1952: the role of influenza and pollution. Environ Health Perspect. 2004 Jan;112(1):6-8.
 Epstein L. Fifty years since Silent Spring. Annu Rev Phytopathol. 2014;52:377-402. doi: 10.1146/annurev-phyto-102313-045900. Epub 2014 Jun 16.
 Gay H. Before and after Silent Spring: from chemical pesticides to biological control and integrated pest management--Britain, 1945-1980. Ambix. 2012 Jul;59(2):88-108.
 Our World In Data. AIr Pollutoin. CC BY-SA copyright. Created by Hannah Ritchie and Max Roser. No changes made to the material. Lisence link: https://creativecommons.org/licenses/by-sa/4.0/deed.en_US
 Brimblecombe, P. London Air Pollution, 1500-1900. Atmospheric Environment. 1977 (11): 1157–1162.
 Smith, SJ, van Aardenne, J ... Delgado Arias S. Anthropogenic sulfur dioxide emissions: 1850–2005. 2011 Atmos. Chem. Phys., (11): 1101-1116
 Kao LW1, Nañagas KA. Carbon monoxide poisoning. Med Clin North Am. 2005 Nov;89(6):1161-94.
 Hanely ME, Patel PH. Carbon Monoxide Toxicity. StatPearls Publishing.
 Hampson NB. Carboxyhemoglobin: a primer for clinicians. Undersea Hyperb Med. 2018 Mar-Apr;45(2):165-171.
 Otterness K, Ahn C. Emergency department management of smoke inhalation injury in adults. Emerg Med Pract. 2018 Mar;20(3):1-24. Epub 2018 Mar 1.
 Gozubuyuk AA, Dag H, ... Arica V. Epidemiology, pathophysiology, clinical evaluation, and treatment of carbon monoxide poisoning in child, infant, and fetus. North Clin Istanb. 2017 May 10;4(1):100-107. doi: 10.14744/nci.2017.49368. eCollection 2017.
 Eizadi-Mood N, Alfred S, ... Moghadam AS. Comparison of arterial and capillary blood gas values in poisoning department assessment. Hum Exp Toxicol. 2009 Oct;28(10):665-70. doi: 10.1177/0960327109107001. Epub 2009 Sep 10.
 AuthorsBuboltz JB, Robins M. Hyperbaric, Carbon Monoxide Toxicity. StatPearls Publishing; 2018.
 Akcan Yildiz L, Gultekingil A, ... Teksam O. Predictors of Severe Clinical Course in Children With Carbon Monoxide Poisoning. Pediatr Emerg Care. 2018 Aug 13. doi: 10.1097/PEC.0000000000001580.
 Rose JJ, Nouraie M, ... Gladwin MT. Clinical Outcomes and Mortality Impact of Hyperbaric Oxygen Therapy in Patients With Carbon Monoxide Poisoning. Crit Care Med. 2018 Jul;46(7):e649-e655. doi: 10.1097/CCM.0000000000003135.
 Salvi A, Patki G, Liu H, Salim S. Psychological Impact of Vehicle Exhaust Exposure: Insights from an Animal Model. Sci Rep. 2017 Aug 16;7(1):8306. doi: 10.1038/s41598-017-08859-1.
 Hudda N, Fruin SA. Carbon dioxide accumulation inside vehicles: The effect of ventilation and driving conditions. Sci Total Environ. 2018 Jan 1;610-611:1448-1456. doi: 10.1016/j.scitotenv.2017.08.105. Epub 2017 Sep 1.
 Chiu CF, Chen MH, Chang FH. Carbon Dioxide Concentrations and Temperatures within Tour Buses under Real-Time Traffic Conditions. PLoS One. 2015 Apr 29;10(4):e0125117. doi: 10.1371/journal.pone.0125117. eCollection 2015.
 Lee GW, Bae MJ,... Lim YW. Decreased blood pressure associated with in-vehicle exposure to carbon monoxide in Korean volunteers. Environ Health Prev Med. 2017 Apr 5;22(1):34. doi: 10.1186/s12199-017-0622-y.
 Hampson NB, Holm JR, Courtney TG. Garage carbon monoxide levels from sources commonly used in intentional poisoning. Undersea Hyperb Med. 2017 Jan-Feb;44(1):11-15.
 Nayor M, Enserro DM, ... Seshadri S. Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study. Stroke. 2016 Feb;47(2):383-9. doi: 10.1161/STROKEAHA.115.010405. Epub 2015 Dec 22.
 Levy RJ. Carbon monoxide pollution and neurodevelopment: A public health concern. Neurotoxicol Teratol. 2015 May-Jun;49:31-40. doi: 10.1016/j.ntt.2015.03.001. Epub 2015 Mar 13.
 Barn P, Giles L, ... Kosatsky T. A review of the experimental evidence on the toxicokinetics of carbon monoxide: the potential role of pathophysiology among susceptible groups. Environ Health. 2018 Feb 5;17(1):13. doi: 10.1186/s12940-018-0357-2.
 Lee FY, Chen WK, Lin CL, Kao CH. Carbon monoxide poisoning and subsequent cardiovascular disease risk: a nationwide population-based cohort study. Medicine (Baltimore). 2015 Mar;94(10):e624. doi: 10.1097/MD.0000000000000624.
 Lai CY, Huang YW, ... Kao CH. Patients With Carbon Monoxide Poisoning and Subsequent Dementia: A Population-Based Cohort Study. Medicine (Baltimore). 2016 Jan;95(1):e2418. doi: 10.1097/MD.0000000000002418.
 Wong CS, Lin YC, ... Wu MY. Increased Long-Term Risk of Dementia in Patients With Carbon Monoxide Poisoning: A Population-Based Study. Medicine (Baltimore). 2016 Jan;95(3):e2549. doi: 10.1097/MD.0000000000002549.
 Liu C, Yin P, ... Zhou M. Ambient carbon monoxide and cardiovascular mortality: a nationwide time-series analysis in 272 cities in China. Lancet Planet Health. 2018 Jan;2(1):e12-e18. doi: 10.1016/S2542-5196(17)30181-X. Epub 2018 Jan 9.
 Bartington SE, Bakolis I, ... Ayres JG. Patterns of domestic exposure to carbon monoxide and particulate matter in households using biomass fuel in Janakpur, Nepal. Environ Pollut. 2017 Jan;220(Pt A):38-45. doi: 10.1016/j.envpol.2016.08.074. Epub 2016 Oct 1.
 Mukhopadhyay S, Hirsch A, ... Orr M. Surveillance of carbon monoxide-related incidents - Implications for prevention of related illnesses and injuries, 2005-2014. Am J Emerg Med. 2018 Oct;36(10):1837-1844. doi: 10.1016/j.ajem.2018.02.011. Epub 2018 Feb 13.
 Watt S, Prado CE, Crowe SF. Immediate and Delayed Neuropsychological Effects of Carbon Monoxide Poisoning: A Meta-analysis. J Int Neuropsychol Soc. 2018 Apr;24(4):405-415. doi: 10.1017/S1355617717001035. Epub 2017 Oct 30.
 Hampson NB. Cost of accidental carbon monoxide poisoning: A preventable expense. Prev Med Rep. 2015 Dec 3;3:21-4. doi: 10.1016/j.pmedr.2015.11.010. eCollection 2016 Jun.
 Reboul C, Boissière J, ... Richard S. Carbon monoxide pollution aggravates ischemic heart failure through oxidative stress pathway. Sci Rep. 2017 Jan 3;7:39715. doi: 10.1038/srep39715.
 André L, Gouzi F, ... Cazorla O. Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress. Basic Res Cardiol. 2011 Nov;106(6):1235-46. doi: 10.1007/s00395-011-0211-y. Epub 2011 Aug 6.
 Huang CC, Ho CH, ... Guo HR. Increased risk for diabetes mellitus in patients with carbon monoxide poisoning. Oncotarget. 2017 Jun 29;8(38):63680-63690. doi: 10.18632/oncotarget.18887. eCollection 2017 Sep 8.
 Lin CW, Chen WK, ... Kao CH. Association between ischemic stroke and carbon monoxide poisoning: A population-based retrospective cohort analysis. Eur J Intern Med. 2016 Apr;29:65-70. doi: 10.1016/j.ejim.2015.11.025. Epub 2015 Dec 17.
 McKenzie LB, Roberts KJ,... Gielen AC. Distribution and Evaluation of a Carbon Monoxide Detector Intervention in Two Settings: Emergency Department and Urban Community. J Environ Health. 2017 May;79(9):24-30.
 Wheeler-Martin K, Soghoian S, ... Hoffman RS. Impact of Mandatory Carbon Monoxide Alarms: An Investigation of the Effects on Detection and Poisoning Rates in New York City. Am J Public Health. 2015 Aug;105(8):1623-9. doi: 10.2105/AJPH.2015.302577. Epub 2015 Jun 11.
 Wong CS, Lin YC, ... Wu MY. Increased long-term risk of major adverse cardiovascular events in patients with carbon monoxide poisoning: A population-based study in Taiwan. PLoS One. 2017 Apr 25;12(4):e0176465. doi: 10.1371/journal.pone.0176465. eCollection 2017.
 Ozyurt A, Karpuz D, ... Hallioglu O. Effects of Acute Carbon Monoxide Poisoning on ECG and Echocardiographic Parameters in Children. Cardiovasc Toxicol. 2017 Jul;17(3):326-334. doi: 10.1007/s12012-016-9389-4.
 Sabzwari SR1, Fatmi Z. Comparison of exhaled carbon monoxide levels among commuters and roadside vendors in an urban and a suburban population in Pakistan. Environ Monit Assess. 2011 Sep;180(1-4):399-408. doi: 10.1007/s10661-010-1795-7. Epub 2010 Dec 2.
 Liu H, Tian Y, ... Hu Y. Association of short-term exposure to ambient carbon monoxide with hospital admissions in China. Sci Rep. 2018 Sep 6;8(1):13336. doi: 10.1038/s41598-018-31434-1.
 Eichhorn L, Michaelis D, ... Tetzlaff K. Carbon monoxide poisoning from waterpipe smoking: a retrospective cohort study. Clin Toxicol (Phila). 2018 Apr;56(4):264-272. doi: 10.1080/15563650.2017.1375115. Epub 2017 Sep 14.
 Maga M, Janik MK, ... Niżankowski R. Influence of air pollution on exhaled carbon monoxide levels in smokers and non-smokers. A prospective cross-sectional study. Environ Res. 2017 Jan;152:496-502. doi: 10.1016/j.envres.2016.09.004. Epub 2016 Oct 4.
 Tian L, Ho KF, ... Yu IT. Ambient carbon monoxide and the risk of hospitalization due to chronic obstructive pulmonary disease. Am J Epidemiol. 2014 Dec 15;180(12):1159-67. doi: 10.1093/aje/kwu248. Epub 2014 Dec 5.
 Lawin H, Ayi Fanou L, ... Sanni A. Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution. BMC Public Health. 2017 Apr 17;17(1):320. doi: 10.1186/s12889-017-4243-6.
 Huang CC, Ho CH, ... Guo HR. Hyperbaric Oxygen Therapy Is Associated With Lower Short- and Long-Term Mortality in Patients With Carbon Monoxide Poisoning. Chest. 2017 Nov;152(5):943-953. doi: 10.1016/j.chest.2017.03.049. Epub 2017 Apr 17.
 Dreyer-Andersen N, Almeida AS, ... Meyer M. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells. PLoS One. 2018 Jan 16;13(1):e0191207. doi: 10.1371/journal.pone.0191207. eCollection 2018.
 Quinn AK, Ae-Ngibise KA, ... Asante KP. Association of Carbon Monoxide exposure with blood pressure among pregnant women in rural Ghana: Evidence from GRAPHS. Int J Hyg Environ Health. 2016 Mar;219(2):176-83. doi: 10.1016/j.ijheh.2015.10.004. Epub 2015 Nov 10.
 Yadav R, Sahu LK, ... Jaaffrey SNA. Ambient particulate matter and carbon monoxide at an urban site of India: Influence of anthropogenic emissions and dust storms. Environ Pollut. 2017 Jun;225:291-303. doi: 10.1016/j.envpol.2017.01.038. Epub 2017 Mar 25.
 Klepac P, Locatelli I, ... Kukec A. Ambient air pollution and pregnancy outcomes: A comprehensive review and identification of environmental public health challenges. Environ Res. 2018 Nov;167:144-159. doi: 10.1016/j.envres.2018.07.008. Epub 2018 Jul 5.
 Kim J, Han Y, ... Ahn K. Association of carbon monoxide levels with allergic diseases in children. Allergy Asthma Proc. 2016 Jan-Feb;37(1):e1-7. doi: 10.2500/aap.2016.37.3918.
 Li S, Guo Y, Williams G. Acute Impact of Hourly Ambient Air Pollution on Preterm Birth. Environ Health Perspect. 2016 Oct;124(10):1623-1629. Epub 2016 Apr 29.
 Alhanti BA, Chang HH, ... Sarnat SE. Ambient air pollution and emergency department visits for asthma: a multi-city assessment of effect modification by age. J Expo Sci Environ Epidemiol. 2016 Mar-Apr;26(2):180-8. doi: 10.1038/jes.2015.57. Epub 2015 Sep 9.
 Darby S, Hill D, ... Doll R. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ. 2005 Jan 29;330(7485):223. Epub 2004 Dec 21.
 Field RW, Steck DJ,... Lynch CF. Residential radon gas exposure and lung cancer: the Iowa Radon Lung Cancer Study. Am J Epidemiol. 2000 Jun 1;151(11):1091-102.
 Environmental Protection Agency. Assessment of Risks from Radon in Homes EPA 402-R-03-003.
 National Research Council (US) Committee on Risk Assessment of Exposure to Radon in Drinking Water. Risk Assessment of Radon in Drinking Water. Washington (DC): National Academies Press (US); 1999.
 Al-Zoughool M, Krewski D.Health effects of radon: a review of the literature. Int J Radiat Biol. 2009 Jan;85(1):57-69. doi: 10.1080/09553000802635054.
 Turner MC, Krewski D, ... Thun MJ. Radon and lung cancer in the American Cancer Society cohort. Cancer Epidemiol Biomarkers Prev. 2011 Mar;20(3):438-48. doi: 10.1158/1055-9965.EPI-10-1153. Epub 2011 Jan 6.
 Turner MC, Krewski D, Chen Y, Pope CA 3rd, Gapstur SM, Thun MJ. Radon and COPD mortality in the American Cancer Society Cohort. Eur Respir J. 2012 May;39(5):1113-9. doi: 10.1183/09031936.00058211. Epub 2011 Oct 17.
 Peterson E, Aker A, Kim J, Li Y, Brand K, Copes R. Lung cancer risk from radon in Ontario, Canada: how many lung cancers can we prevent? Cancer Causes Control. 2013 Nov;24(11):2013-20. doi: 10.1007/s10552-013-0278-x. Epub 2013 Aug 28.
 Vienneau D1,2, de Hoogh K1,2, ... Röösli M. Effects of Radon and UV Exposure on Skin Cancer Mortality in Switzerland. Environ Health Perspect. 2017 Jun 16;125(6):067009. doi: 10.1289/EHP825.
 Groves-Kirkby CJ, Denman AR, ... Rogers S. Is environmental radon gas associated with the incidence of neurodegenerative conditions? A retrospective study of multiple sclerosis in radon affected areas in England and Wales. J Environ Radioact. 2016 Apr;154:1-14. doi: 10.1016/j.jenvrad.2015.12.003. Epub 2016 Jan 23.
 Peckham EC, Scheurer ME, ... Lupo PJ. Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995-2011. Int J Environ Res Public Health. 2015 Sep 25;12(10):12110-26. doi: 10.3390/ijerph121012110.
 Auvinen A, Salonen L, ... Kurttio P. Radon and other natural radionuclides in drinking water and risk of stomach cancer: a case-cohort study in Finland. Int J Cancer. 2005 Mar 10;114(1):109-13.
 Darby S, Hill D, ... Doll R. Residential radon and lung cancer--detailed results of a collaborative analysis of individual data on 7148 persons with lung cancer and 14,208 persons without lung cancer from 13 epidemiologic studies in Europe. Scand J Work Environ Health. 2006;32 Suppl 1:1-83.
 Laurier D, Valenty M, Tirmarche M. Radon exposure and the risk of leukemia: a review of epidemiological studies. Health Phys. 2001 Sep;81(3):272-88.
 Ajrouche R, Ielsch G, ... Le Tertre A. Quantitative Health Risk Assessment of Indoor Radon: A Systematic Review. Radiat Prot Dosimetry. 2017 Nov 1;177(1-2):69-77. doi: 10.1093/rpd/ncx152.
 Torres-Durán M, Barros-Dios JM, Fernández-Villar A, Ruano-Ravina A. Residential radon and lung cancer in never smokers. A systematic review. Cancer Lett. 2014 Apr 1;345(1):21-6. doi: 10.1016/j.canlet.2013.12.010. Epub 2013 Dec 11.
 Vogeltanz-Holm N, Schwartz GG. Radon and lung cancer: What does the public really know? J Environ Radioact. 2018 Dec;192:26-31. doi: 10.1016/j.jenvrad.2018.05.017. Epub 2018 Jun 5.
 Garcia-Rodriguez JA. Radon gas-the hidden killer: What is the role of family doctors? Can Fam Physician. 2018 Jul;64(7):496-501.
 Ravina AR, Dacosta-Urbieta A, ... Kelsey KT. Radon exposure and tumors of the central nervous system. Gaceta Sanitaria 2017.
 Ruano-Ravina A, Aragonés N ... Barros-Dios JM. Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain). Sci Rep. 2017 Jun 15;7(1):3595. doi: 10.1038/s41598-017-03938-9.
 EPA. Home Buyer’s and Seller’s Guide to Radon. EPA 402/K-13/002 March 2018.
 World Health Organization. Handbook on Indoor Radon: A Public Health Perspective, 2009.
 Faustini A, Rapp R, Forastiere F. Nitrogen dioxide and mortality: review and meta-analysis of long-term studies. Eur Respir J. 2014 Sep;44(3):744-53. doi: 10.1183/09031936.00114713. Epub 2014 Feb 20.
 Eisner MD, Anthonisen N, ... Environmental and Occupational Health Assembly. An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Sep 1;182(5):693-718. doi: 10.1164/rccm.200811-1757ST.
 Zhang Z, Wang J, Lu W. Exposure to nitrogen dioxide and chronic obstructive pulmonary disease (COPD) in adults: a systematic review and meta-analysis. Environ Sci Pollut Res Int. 2018 May;25(15):15133-15145. doi: 10.1007/s11356-018-1629-7. Epub 2018 Mar 20.
 Gong H Jr, Linn WS, ... Sioutas C. Respiratory responses to exposures with fine particulates and nitrogen dioxide in the elderly with and without COPD. Inhal Toxicol. 2005 Mar;17(3):123-32.
 Belanger K, Holford TR, ... Leaderer BP. Household levels of nitrogen dioxide and pediatric asthma severity. Epidemiology. 2013 Mar;24(2):320-30. doi: 10.1097/EDE.0b013e318280e2ac.
 Health Effects Institute. Traffic-Related Air Pollution: A Critical Review of the Literature on Emissions, Exposure, and Health Effects. 2010.
 Hoek G, Krishnan RM, ... Kaufman JD. Long-term air pollution exposure and cardio- respiratory mortality: a review. Environ Health. 2013 May 28;12(1):43. doi: 10.1186/1476-069X-12-43.
 Atkinson RW, Butland BK, Anderson HR, Maynard RL. Long-term Concentrations of Nitrogen Dioxide and Mortality: A Meta-analysis of Cohort Studies. Epidemiology. 2018 Jul;29(4):460-472. doi: 10.1097/EDE.0000000000000847.
 Sun J, Barnes AJ, He D, Wang M, Wang J. Systematic Review and Meta-Analysis of the Association between Ambient Nitrogen Dioxide and Respiratory Disease in China. Int J Environ Res Public Health. 2017 Jun 16;14(6). pii: E646. doi: 10.3390/ijerph14060646.
 Mills IC, Atkinson RW, ... Anderson HR. Quantitative systematic review of the associations between short-term exposure to nitrogen dioxide and mortality and hospital admissions. BMJ Open. 2015 May 11;5(5):e006946. doi: 10.1136/bmjopen-2014-006946.
 Hamra GB, Laden F, ... Loomis D. Lung Cancer and Exposure to Nitrogen Dioxide and Traffic: A Systematic Review and Meta-Analysis. Environ Health Perspect. 2015 Nov;123(11):1107-12. doi: 10.1289/ehp.1408882. Epub 2015 Apr 14.
 Luo K, Li R,... Xu Q. Acute Effects of Nitrogen Dioxide on Cardiovascular Mortality in Beijing: An Exploration of Spatial Heterogeneity and the District-specific Predictors. Sci Rep. 2016 Dec 2;6:38328. doi: 10.1038/srep38328.
 Cepeda M, Schoufour J, ... Franco OH. Levels of ambient air pollution according to mode of transport: a systematic review. Lancet Public Health. 2017 Jan;2(1):e23-e34. doi: 10.1016/S2468-2667(16)30021-4. Epub 2016 Nov 26.
 Yang BY, Qian Z, ... Dong GH. Global association between ambient air pollution and blood pressure: A systematic review and meta-analysis. Environ Pollut. 2018 Apr;235:576-588. doi: 10.1016/j.envpol.2018.01.001. Epub 2018 Jan 11.
 German Environment Agency. Quantifizierung von umweltbedingten Krankheitslasten aufgrund der Stickstoffdioxid-Exposition in Deutschland, 2018.
 UK Department For Environment, Food, And Rural Affairs. Draft plans to improve air quality in the UK Tackling nitrogen dioxide in our towns and cities. 2015.
 Committee on the Medical Effects of Air Pollutants.
 Zhao T, Markevych I, ... Heinrich J. Ambient ozone exposure and mental health: A systematic review of epidemiological studies. Environ Res. 2018 Aug;165:459-472. doi: 10.1016/j.envres.2018.04.015. Epub 2018 May 1.
 Mendola P, Ha S, ... Liu D. Chronic and Acute Ozone Exposure in the Week Prior to Delivery Is Associated with the Risk of Stillbirth. Int J Environ Res Public Health. 2017 Jul 6;14(7). pii: E731. doi: 10.3390/ijerph14070731.
 Atkinson RW, Butland BK, ... Anderson HR. Long-term exposure to ambient ozone and mortality: a quantitative systematic review and meta-analysis of evidence from cohort studies. BMJ Open. 2016 Feb 23;6(2):e009493. doi: 10.1136/bmjopen-2015-009493.
 Yin P, Chen R, ... Kan H. Ambient Ozone Pollution and Daily Mortality: A Nationwide Study in 272 Chinese Cities. Environ Health Perspect. 2017 Nov 21;125(11):117006. doi: 10.1289/EHP1849.
 Bell ML, Zanobetti A, Dominici F. Who is more affected by ozone pollution? A systematic review and meta-analysis. Am J Epidemiol. 2014 Jul 1;180(1):15-28. doi: 10.1093/aje/kwu115. Epub 2014 May 28.
 Koman PD, Mancuso P. Ozone Exposure, Cardiopulmonary Health, and Obesity: A Substantive Review. Chem Res Toxicol. 2017 Jul 17;30(7):1384-1395. doi: 10.1021/acs.chemrestox.7b00077. Epub 2017 Jun 15.
 Jerrett M, Burnett RT, ... Thun M. Long-term ozone exposure and mortality. N Engl J Med. 2009 Mar 12;360(11):1085-95. doi: 10.1056/NEJMoa0803894.
 Goodman JE, Zu K, ... Sax SN. Short-term ozone exposure and asthma severity: Weight-of-evidence analysis. Environ Res. 2018 Jan;160:391-397. doi: 10.1016/j.envres.2017.10.018.
 Shah AS, Langrish JP, ... Mills NL. Global association of air pollution and heart failure: a systematic review and meta-analysis. Lancet. 2013 Sep 21;382(9897):1039-48. doi: 10.1016/S0140-6736(13)60898-3. Epub 2013 Jul 10.
 Zhang B, Zhao J, Yang ... Yang S. Ozone and Other Air Pollutants and the Risk of Congenital Heart Defects. Sci Rep. 2016 Oct 18;6:34852. doi: 10.1038/srep34852.
 Srebot V, Gianicolo EA, Rainaldi G, Trivella MG, Sicari R. Ozone and cardiovascular injury. Cardiovasc Ultrasound. 2009 Jun 24;7:30. doi: 10.1186/1476-7120-7-30.
 Goodman JE, Prueitt RL, ... Venditti FJ. Ozone exposure and systemic biomarkers: Evaluation of evidence for adverse cardiovascular health impacts. Crit Rev Toxicol. 2015 May;45(5):412-52. doi: 10.3109/10408444.2015.1031371.
 Mirowsky JE, Carraway MS, ... Devlin RB. Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. Environ Health. 2017 Nov 21;16(1):126. doi: 10.1186/s12940-017-0335-0.
 WHO Regional Office Europe. Review of evidence on health aspects of air pollution – REVIHAAP Project: Technical Report: BHealth effects of ozone.
 Medina-Ramón M, Schwartz J. Who is more vulnerable to die from ozone air pollution? Epidemiology. 2008 Sep;19(5):672-9. doi: 10.1097/EDE.0b013e3181773476.
 Sawyer K, Brown JS, Hazucha MJ, Bennett WD. The effect of exercise on nasal uptake of ozone in healthy human adults. J Appl Physiol (1985). 2007 Apr;102(4):1380-6. Epub 2006 Nov 2.
 Stafoggia M1, Forastiere F, ... Perucci CA; EpiAir Group. Susceptibility factors to ozone-related mortality: a population-based case-crossover analysis. Am J Respir Crit Care Med. 2010 Aug 1;182(3):376-84. doi: 10.1164/rccm.200908-1269OC. Epub 2010 Mar 25.
 Turner MC, Jerrett M, ... Burnett RT. Long-Term Ozone Exposure and Mortality in a Large Prospective Study. Am J Respir Crit Care Med. 2016 May 15;193(10):1134-42. doi: 10.1164/rccm.201508-1633OC.
 Alexeeff SE, Litonjua AA, ... Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest. 2007 Dec;132(6):1890-7. Epub 2007 Oct 9.
 McDonnell WF, Stewart PW, Smith MV. Prediction of ozone-induced lung function responses in humans. Inhal Toxicol. 2010 Feb;22(2):160-8. doi: 10.3109/08958370903089557.
 Lin S, Liu X, Le LH, Hwang SA. Chronic exposure to ambient ozone and asthma hospital admissions among children. Environ Health Perspect. 2008 Dec;116(12):1725-30. doi: 10.1289/ehp.11184. Epub 2008 Sep 10.
 Bell ML, McDermott A, ... Dominici F. Ozone and short-term mortality in 95 US urban communities, 1987-2000. JAMA. 2004 Nov 17;292(19):2372-8.
 Gryparis A, Forsberg B, ... Dörtbudak Z. Acute effects of ozone on mortality from the "air pollution and health: a European approach" project. Am J Respir Crit Care Med. 2004 Nov 15;170(10):1080-7. Epub 2004 Jul 28.
 Bell ML, Dominici F, Samet JM. A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution study. Epidemiology. 2005 Jul;16(4):436-45.
 Levy JI, Chemerynski SM, Sarnat JA. Ozone exposure and mortality: an empiric bayes metaregression analysis. Epidemiology. 2005 Jul;16(4):458-68.
 Ito K, De Leon SF, Lippmann M. Associations between ozone and daily mortality: analysis and meta-analysis. Epidemiology. 2005 Jul;16(4):446-57.
 Zanobetti A, Schwartz J. Mortality displacement in the association of ozone with mortality: an analysis of 48 cities in the United States. Am J Respir Crit Care Med. 2008 Jan 15;177(2):184-9. Epub 2007 Oct 11.
 Samoli E, Zanobetti A, ... Katsouyanni K. The temporal pattern of mortality responses to ambient ozone in the APHEA project. J Epidemiol Community Health. 2009 Dec;63(12):960-6. doi: 10.1136/jech.2008.084012. Epub 2009 Jul 30.
 Gong H, Wong R,... Prasad SB. Cardiovascular effects of ozone exposure in human volunteers. Am J Respir Crit Care Med. 1998 Aug;158(2):538-46.
 Rich DQ, Balmes JR, ... Bromberg PA. Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES). Environ Int. 2018 Oct;119:193-202. doi: 10.1016/j.envint.2018.06.014. Epub 2018 Jul 4.
 Frampton MW, Pietropaoli A, ... Utell MJ. Cardiovascular effects of ozone in healthy subjects with and without deletion of glutathione-S-transferase M1. Inhal Toxicol. 2015 Feb;27(2):113-9. doi: 10.3109/08958378.2014.996272.
 Stenfors N, Pourazar J, ... Sandström T. Effect of ozone on bronchial mucosal inflammation in asthmatic and healthy subjects. Respir Med. 2002 May;96(5):352-8.
 Golden JA, Nadel JA, Boushey HA. Bronchial hyperirritability in healthy subjects after exposure to ozone. Am Rev Respir Dis. 1978 Aug;118(2):287-94.
 Di Q, Dai L, ... Dominici F. Association of Short-term Exposure to Air Pollution With Mortality in Older Adults. JAMA. 2017 Dec 26;318(24):2446-2456. doi: 10.1001/jama.2017.17923.
 Parker JD, Akinbami LJ, Woodruff TJ. Air pollution and childhood respiratory allergies in the United States. Environ Health Perspect. 2009 Jan;117(1):140-7. doi: 10.1289/ehp.11497. Epub 2008 Sep 30.
 Frank U, Ernst D. Effects of NO2 and Ozone on Pollen Allergenicity. Front Plant Sci. 2016 Feb 4;7:91. doi: 10.3389/fpls.2016.00091. eCollection 2016.
 Khatri SB, Holguin FC, ... Teague WG. Association of ambient ozone exposure with airway inflammation and allergy in adults with asthma. J Asthma. 2009 Oct;46(8):777-85.
 Takizawa H. Impact of air pollution on allergic diseases. Korean J Intern Med. 2011 Sep;26(3):262-73. doi: 10.3904/kjim.2011.26.3.262. Epub 2011 Sep 13.
 Zhang Q, Qiu Z, Chung KF, Huang SK. Link between environmental air pollution and allergic asthma: East meets West. J Thorac Dis. 2015 Jan;7(1):14-22. doi: 10.3978/j.issn.2072-1439.2014.12.07.
 Rufo JC, Madureira J, Fernandes EO, Moreira A. Volatile organic compounds in asthma diagnosis: a systematic review and meta-analysis. Allergy. 2016 Feb;71(2):175-88. doi: 10.1111/all.12793. Epub 2015 Nov 13.
 Ho DX, Kim KH, Sohn JR, Oh YH, Ahn JW. Emission rates of volatile organic compounds released from newly produced household furniture products using a large-scale chamber testing method. ScientificWorldJournal. 2011;11:1597-622. doi: 10.1100/2011/650624. Epub 2011 Sep 8.
 Nurmatov UB, Tagiyeva N, Semple S, Devereux G, Sheikh A. Volatile organic compounds and risk of asthma and allergy: a systematic review. Eur Respir Rev. 2015 Mar;24(135):92-101. doi: 10.1183/09059180.00000714.
 Paciência I, Madureira J,... Fernandes Ede O. A systematic review of evidence and implications of spatial and seasonal variations of volatile organic compounds (VOC) in indoor human environments. J Toxicol Environ Health B Crit Rev. 2016;19(2):47-64. doi: 10.1080/10937404.2015.1134371. Epub 2016 May 10.
 Zhang J, Smith KR. Indoor air pollution: a global health concern. Br Med Bull. 2003;68:209-25.
 Franklin PJ. Indoor air quality and respiratory health of children. Paediatr Respir Rev. 2007 Dec;8(4):281-6. Epub 2007 Oct 31.
 Dales R, Raizenne M. Residential exposure to volatile organic compounds and asthma. J Asthma. 2004;41(3):259-70.
 Krzyzanowski M, Quackenboss JJ, Lebowitz MD. Chronic respiratory effects of indoor formaldehyde exposure. Environ Res. 1990 Aug;52(2):117-25.
 Jaakkola JJ, Verkasalo PK, Jaakkola N. Plastic wall materials in the home and respiratory health in young children. Am J Public Health. 2000 May;90(5):797-9.
 Rumchev K, Spickett J,... Stick S. Association of domestic exposure to volatile organic compounds with asthma in young children. Thorax. 2004 Sep;59(9):746-51.
 Rumchev KB, Spickett JT, ... Stick SM.Domestic exposure to formaldehyde significantly increases the risk of asthma in young children. Eur Respir J. 2002 Aug;20(2):403-8.
 Brown SK. Chamber assessment of formaldehyde and VOC emissions from wood-based panels. Indoor Air. 1999 Sep;9(3):209-15.
 Wang JX, Shen J, Lei CS, Feng Q. Volatile organic compound and formaldehyde emissions from Populus davidiana wood treated with low molecular weight urea-formaldehyde resin. J Environ Biol. 2014 Sep;35(5):989-94.
 Guo H, Kwok NH, ... Li YS. Formaldehyde and volatile organic compounds in Hong Kong homes: concentrations and impact factors. Indoor Air. 2009 Jun;19(3):206-17. doi: 10.1111/j.1600-0668.2008.00580.x. Epub 2009 Feb 7.
 Lee K, Choi JH,... Son BS. Indoor levels of volatile organic compounds and formaldehyde from emission sources at elderly care centers in Korea. PLoS One. 2018 Jun 7;13(6):e0197495. doi: 10.1371/journal.pone.0197495. eCollection 2018.
 Wolkoff P, Wilkins CK, Clausen PA, Nielsen GD. Organic compounds in office environments - sensory irritation, odor, measurements and the role of reactive chemistry. Indoor Air. 2006 Feb;16(1):7-19.
 Joshi SM. The sick building syndrome. Indian J Occup Environ Med. 2008 Aug;12(2):61-4. doi: 10.4103/0019-5278.43262.
 Dick FD. Solvent neurotoxicity. Occup Environ Med. 2006 Mar;63(3):221-6, 179.
 Shuai J, Kim S, ... Yang W. Health risk assessment of volatile organic compounds exposure near Daegu dyeing industrial complex in South Korea. BMC Public Health. 2018 Apr 20;18(1):528. doi: 10.1186/s12889-018-5454-1.
 Ma CM, Lin LY,... Chuang KJ. Volatile organic compounds exposure and cardiovascular effects in hair salons. Occup Med (Lond). 2010 Dec;60(8):624-30. doi: 10.1093/occmed/kqq128. Epub 2010 Sep 5.
 St Helen G, Jacob P, ... Benowitz NL. Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer Epidemiol Biomarkers Prev. 2014 Dec;23(12):2774-82. doi: 10.1158/1055-9965.EPI-14-0548. Epub 2014 Nov 14.
 Yoon HI, Hong YC, ... Cheong HK. Exposure to volatile organic compounds and loss of pulmonary function in the elderly. Eur Respir J. 2010 Dec;36(6):1270-6. doi: 10.1183/09031936.00153509. Epub 2010 Mar 29.
 Elliott L, Longnecker MP, Kissling GE, London SJ. Volatile organic compounds and pulmonary function in the Third National Health and Nutrition Examination Survey, 1988-1994. Environ Health Perspect. 2006 Aug;114(8):1210-4.
 Ran J, Qiu H, Sun S, Yang A, Tian L. Are ambient volatile organic compounds environmental stressors for heart failure? Environ Pollut. 2018 Nov;242(Pt B):1810-1816. doi: 10.1016/j.envpol.2018.07.086. Epub 2018 Jul 27.
 Lang AL, Beier JI. Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk. Biol Chem. 2018 Oct 25;399(11):1237-1248. doi: 10.1515/hsz-2017-0324.
 Liu J, Drane W, Liu X, Wu T. Examination of the relationships between environmental exposures to volatile organic compounds and biochemical liver tests: application of canonical correlation analysis. Environ Res. 2009 Feb;109(2):193-9. doi: 10.1016/j.envres.2008.11.002. Epub 2008 Dec 30.
 Malaguarnera G, Cataudella E, ... Malaguarnera M. Toxic hepatitis in occupational exposure to solvents. World J Gastroenterol. 2012 Jun 14;18(22):2756-66. doi: 10.3748/wjg.v18.i22.2756.
 Chang TY, Huang KH, ... Bao BY. Exposure to volatile organic compounds and kidney dysfunction in thin film transistor liquid crystal display (TFT-LCD) workers. J Hazard Mater. 2010 Jun 15;178(1-3):934-40. doi: 10.1016/j.jhazmat.2010.02.027. Epub 2010 Feb 18.
 Meinardi S, Jin KB, ... Vaziri ND. Exhaled breath and fecal volatile organic biomarkers of chronic kidney disease. Biochim Biophys Acta. 2013 Mar;1830(3):2531-7.
 Batterman S, Su FC, Li S, Mukherjee B, Jia C; HEI Health Review Committee. Personal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data. Res Rep Health Eff Inst. 2014 Jun;(181):3-63.
 Gallagher M, Wysocki CJ, ... Preti G. Analyses of volatile organic compounds from human skin. Br J Dermatol. 2008 Sep;159(4):780-91. doi: 10.1111/j.1365-2133.2008.08748.x. Epub 2008 Jul 14.
 Gostner JM, Zeisler J, ... Überall F. Cellular reactions to long-term volatile organic compound (VOC) exposures. Sci Rep. 2016 Dec 1;6:37842. doi: 10.1038/srep37842.
 Creta M, Poels K, ... Vanoirbeek JAJ. A Method to Quantitatively Assess Dermal Exposure to Volatile Organic Compounds. Ann Work Expo Health. 2017 Oct 1;61(8):975-985. doi: 10.1093/annweh/wxx054.
 World Health Organization. Burden of disease from Ambient Air Pollution for 2012.
 Lim SS, Vos T, ... Memish ZA. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15;380(9859):2224-60. doi: 10.1016/S0140-6736(12)61766-8.
 Schulz H. Fine particulate matter - a health hazard for lungs and other organs?. Pneumologie. 2006 Oct;60(10):611-5.
 Yoshizaki K, Brito JM, ... Macchione M. The effects of particulate matter on inflammation of respiratory system: Differences between male and female. Sci Total Environ. 2017 May 15;586:284-295. doi: 10.1016/j.scitotenv.2017.01.221. Epub 2017 Feb 4.
 Tamagawa E, Bai N, ... van Eeden SF. Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L79-85. doi: 10.1152/ajplung.00048.2007. Epub 2008 May 9.
 Grunig G, Marsh LM, ... Park SH. Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature. Pulm Circ. 2014 Mar;4(1):25-35. doi: 10.1086/674902.
 Seaton A, Soutar A, ... Stout R. Particulate air pollution and the blood. Thorax. 1999 Nov;54(11):1027-32.
 Sørensen M, Daneshvar B, ... Loft S. Personal PM2.5 exposure and markers of oxidative stress in blood. Environ Health Perspect. 2003 Feb;111(2):161-6.
 Wang T, Chiang ET, ... Garcia JG. Particulate matter disrupts human lung endothelial barrier integrity via ROS- and p38 MAPK-dependent pathways. Am J Respir Cell Mol Biol. 2010 Apr;42(4):442-9. doi: 10.1165/rcmb.2008-0402OC. Epub 2009 Jun 11.
 Wang T, Wang L, ... Garcia JG. Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation. Part Fibre Toxicol. 2012 Aug 29;9:35. doi: 10.1186/1743-8977-9-35.
 Zeka A, Zanobetti A, Schwartz J. Short term effects of particulate matter on cause specific mortality: effects of lags and modification by city characteristics. Occup Environ Med. 2005 Oct;62(10):718-25.
 Atkinson RW, Mills IC, Walton HA, Anderson HR. Fine particle components and health--a systematic review and meta-analysis of epidemiological time series studies of daily mortality and hospital admissions. J Expo Sci Environ Epidemiol. 2015 Mar-Apr;25(2):208-14. doi:10.1038/jes.2014.63. Epub 2014 Sep 17.
 Kloog I, Ridgway B, ... Schwartz JD. Long- and short-term exposure to PM2.5 and mortality: using novel exposure models. Epidemiology. 2013 Jul;24(4):555-61. doi:
 Mills IC, Atkinson RW, ... Strachan DP. Distinguishing the associations between daily mortality and hospital admissions and nitrogen dioxide from those of particulate matter: a systematic review and meta-analysis. BMJ Open. 2016 Jul 21;6(7):e010751. doi: 10.1136/bmjopen-2015-010751.
 Pelucchi C, Negri E, ... La Vecchia C. Long-term particulate matter exposure and mortality: a review of European epidemiological studies. BMC Public Health. 2009 Dec 8;9:453. doi: 10.1186/1471-2458-9-453.
 Li T, Yan M, Sun Q, Anderson GB. Mortality risks from a spectrum of causes associated with wide-ranging exposure to fine particulate matter: A case-crossover study in Beijing, China. Environ Int. 2018 Feb;111:52-59. doi: 10.1016/j.envint.2017.10.023. Epub 2017 Nov 22.
 Newell K, Kartsonaki C, Lam KBH, Kurmi OP. Cardiorespiratory health effects of particulate ambient air pollution exposure in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Planet Health. 2017 Dec;1(9):e368-e380. doi: 10.1016/S2542-5196(17)30166-3. Epub 2017 Dec 8.
 Requia WJ, Adams MD, ... Mahmoud M. Global Association of Air Pollution and Cardiorespiratory Diseases: A Systematic Review, Meta-Analysis, and Investigation of Modifier Variables. Am J Public Health. 2018 Apr;108(S2):S123-S130. doi: 10.2105/AJPH.2017.303839. Epub 2017 Oct 26.
 Li J, Sun S, ... Tian L. Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis. 2016 Dec 12;11:3079-3091. doi: 10.2147/COPD.S122282. eCollection 2016.
 Liu Q, Xu C, ... Zhao P. Effect of exposure to ambient PM2.5 pollution on the risk of respiratory tract diseases: a meta-analysis of cohort studies. J Biomed Res. 2017 Jan 19;31(2):130-142. doi: 10.7555/JBR.31.20160071.
 Hamra GB, Guha N, ... Loomis D. Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis. Environ Health Perspect. 2014 Sep;122(9):906-11. doi: 10.1289/ehp.1408092. Epub 2014 Jun 6.
 Roy A, Hu W, Wei F, Korn L, Chapman RS, Zhang JJ. Ambient particulate matter and lung function growth in Chinese children. Epidemiology. 2012 May;23(3):464-72. doi:
 Koenig JQ, Larson TV, ... Pierson WE. Pulmonary function changes in children associated with fine particulate matter. Environ Res. 1993 Oct;63(1):26-38.
 Kim JH, Lim DH, Kim JK, Jeong SJ, Son BK. Effects of particulate matter (PM10) on the pulmonary function of middle-school children. J Korean Med Sci. 2005 Feb;20(1):42-5.
 Chen H, Goldberg MS, Villeneuve PJ. A systematic review of the relation between long-term exposure to ambient air pollution and chronic diseases. Rev Environ Health. 2008 Oct-Dec;23(4):243-97.
 ] Lim YH, Bae HJ, ... Hong YC. Vascular and cardiac autonomic function and PM2.5 constituents among the elderly: A longitudinal study. Sci Total Environ. 2017 Dec 31;607-608:847-854. doi: 10.1016/j.scitotenv.2017.07.077. Epub 2017 Jul 27.
 Kim H, Kim J, ... Chae IH. Cardiovascular Effects of Long-Term Exposure to Air Pollution: A Population-Based Study With 900 845 Person-Years of Follow-up. J Am Heart Assoc. 2017 Nov 8;6(11). pii: e007170. doi: 10.1161/JAHA.117.007170.
 Martinelli N, Olivieri O, Girelli D. Air particulate matter and cardiovascular disease: a narrative review. Eur J Intern Med. 2013 Jun;24(4):295-302. doi: 10.1016/j.ejim.2013.04.001. Epub 2013 May 4.
 Fiordelisi A, Piscitelli P, ... Sorriento D. The mechanisms of air pollution and particulate matter in cardiovascular diseases. Heart Fail Rev. 2017 May;22(3):337-347. doi: 10.1007/s10741-017-9606-7.
 Li H, Cai J, ... Kan H. Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification. Circulation. 2017 Aug 15;136(7):618-627. doi: 10.1161/CIRCULATIONAHA.116.026796.
 Hicken MT, Dvonch JT, Schulz AJ, Mentz G, Max P. Fine particulate matter air pollution and blood pressure: the modifying role of psychosocial stress. Environ Res. 2014 Aug;133:195-203. doi: 10.1016/j.envres.2014.06.001. Epub 2014 Jun 24.
 Borchers AT, Chang C, Eric Gershwin M. Mold and Human Health: a Reality Check. Clin Rev Allergy Immunol. 2017 Jun;52(3):305-322. doi: 10.1007/s12016-017-8601-z.
 Edmondson DA, Nordness ME, Zacharisen MC, Kurup VP, Fink JN. Allergy and "toxic mold syndrome". Ann Allergy Asthma Immunol. 2005 Feb;94(2):234-9.
 Valtonen V. Clinical Diagnosis of the Dampness and Mold Hypersensitivity Syndrome: Review of the Literature and Suggested Diagnostic Criteria. Front Immunol. 2017 Aug 10;8:951. doi: 10.3389/fimmu.2017.00951. eCollection 2017.
 Brewer JH, Thrasher JD, Hooper D. Chronic illness associated with mold and mycotoxins: is naso-sinus fungal biofilm the culprit? Toxins (Basel). 2013 Dec 24;6(1):66-80. doi: 10.3390/toxins6010066.
 Bennett JW1, Klich M. Mycotoxins. Clin Microbiol Rev. 2003 Jul;16(3):497-516.
 Rosenblum Lichtenstein JH, Hsu YH, ... Brain JD. Environmental mold and mycotoxin exposures elicit specific cytokine and chemokine responses. PLoS One. 2015 May 26;10(5):e0126926. doi: 10.1371/journal.pone.0126926. eCollection 2015.
 World Health Organization. WHO guidelines for indoor air quality: dampness and mould.
 Palma N, Cinelli S, ... Dogliotti E. Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress. Chem Res Toxicol. 2007 Jul;20(7):1031-7. Epub 2007 Jun 14.
 Monnet-Tschudi F, Zurich MG, ... Schilter B. The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture. Neurotoxicology. 1999 Feb;20(1):41-8.
 Doi K, Uetsuka K. Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathways. Int J Mol Sci. 2011;12(8):5213-37. doi: 10.3390/ijms12085213. Epub 2011 Aug 15.
 Bossou YM, Serssar Y, ... Achard S. Impact of Mycotoxins Secreted by Aspergillus Molds on the Inflammatory Response of Human Corneal Epithelial Cells. Toxins (Basel). 2017 Jun 22;9(7). pii: E197. doi: 10.3390/toxins9070197.
 Daschner A. An Evolutionary-Based Framework for Analyzing Mold and Dampness-Associated Symptoms in DMHS. Front Immunol. 2017 Jan 9;7:672. doi: 10.3389/fimmu.2016.00672. eCollection 2016.
 Aiko V, Mehta A. Occurrence, detection and detoxification of mycotoxins. J Biosci. 2015 Dec;40(5):943-54.
 Rosenblum Lichtenstein JH, Molina RM, ... Brain JD. Repeated Mouse Lung Exposures to Stachybotrys chartarum Shift Immune Response from Type 1 to Type 2. Am J Respir Cell Mol Biol. 2016 Oct;55(4):521-531.
 Tuuminen T, Rinne KS. Severe Sequelae to Mold-Related Illness as Demonstrated in Two Finnish Cohorts. Front Immunol. 2017 Apr 3;8:382. doi: 10.3389/fimmu.2017.00382. eCollection 2017.
 Bartrip PW. History of asbestos related disease. Postgrad Med J. 2004 Feb;80(940):72-6.
 Lemen RA. Introduction: history of the use of asbestos. Med Lav. 1997 Jul-Aug;88(4):288-92.
 The David Law Firm. Shipyards, a Crucible for Tragedy Part 1: How the war created a monster. 2001.
 Nielsen LS, Bælum J, ... Sherson D. Occupational asbestos exposure and lung cancer--a systematic review of the literature. Arch Environ Occup Health. 2014;69(4):191-206. doi: 10.1080/19338244.2013.863752.
 Kang D, Myung MS, Kim YK, Kim JE. Systematic Review of the Effects of Asbestos Exposure on the Risk of Cancer between Children and Adults. Ann Occup Environ Med. 2013 Jul 8;25(1):10. doi: 10.1186/2052-4374-25-10.
 Wilken D, Velasco Garrido M, Manuwald U, Baur X. Lung function in asbestos-exposed workers, a systematic review and meta-analysis. J Occup Med Toxicol. 2011 Jul 26;6:21. doi: 10.1186/1745-6673-6-21.
 Ngamwong Y, Tangamornsuksan W, ...Lohitnavy M. Additive Synergism between Asbestos and Smoking in Lung Cancer Risk: A Systematic Review and Meta-Analysis. PLoS One. 2015 Aug 14;10(8):e0135798. doi: 10.1371/journal.pone.0135798. eCollection 2015.
 Ollier M, Chamoux A, ... Dutheil F. Chest CT scan screening for lung cancer in asbestos occupational exposure: a systematic review and meta-analysis. Chest. 2014 Jun;145(6):1339-1346. doi: 10.1378/chest.13-2181.
 Neri M, Ugolini D ... Bonassi S. Chemoprevention of asbestos-linked cancers: a systematic review. Anticancer Res. 2012 Mar;32(3):1005-13.
 LaDou J. The asbestos cancer epidemic. Environ Health Perspect. 2004 Mar;112(3):285-90.
 Khalade A, Jaakkola MS, Pukkala E, Jaakkola JJ. Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. Environ Health. 2010 Jun 28;9:31. doi: 10.1186/1476-069X-9-31.
 D'Andrea MA, Reddy GK. Health Risks Associated With Benzene Exposure in Children: A Systematic Review. Glob Pediatr Health. 2018 Aug 17;5:2333794X18789275. doi: 10.1177/2333794X18789275. eCollection 2018.
 Smith MT. Advances in understanding benzene health effects and susceptibility. Annu Rev Public Health. 2010;31:133-48 2 p following 148. doi: 10.1146/annurev.publhealth.012809.103646.
 Gist GL, Burg JR. Benzene--a review of the literature from a health effects perspective. Toxicol Ind Health. 1997 Nov-Dec;13(6):661-714.
 Wiwanitkit V. Benzene exposure and hypertension: an observation. Cardiovasc J Afr. 2007 Jul-Aug;18(4):264-5.
 Wiwanitkit V. Headaches in subjects occupationally exposed to benzene vapors. J Headache Pain. 2008 Aug;9(4):253-4. doi: 10.1007/s10194-008-0041-y. Epub 2008 May 7.
 Edokpolo B, Yu QJ, Connell D. Health risk characterization for exposure to benzene in service stations and petroleum refineries environments using human adverse response data. Toxicol Rep. 2015 Jun 5;2:917-927. doi: 10.1016/j.toxrep.2015.06.004. eCollection 2015.
 Kataria A, Trasande L, Trachtman H. The effects of environmental chemicals on renal function. Nat Rev Nephrol. 2015 Oct;11(10):610-25. doi: 10.1038/nrneph.2015.94. Epub 2015 Jun 23.
 Neghab M, Hosseinzadeh K, Hassanzadeh J. Early Liver and Kidney Dysfunction Associated with Occupational Exposure to Sub-Threshold Limit Value Levels of Benzene, Toluene, and Xylenes in Unleaded Petrol. Saf Health Work. 2015 Dec;6(4):312-6. doi: 10.1016/j.shaw.2015.07.008. Epub 2015 Aug 5.
 Snyder R, Hedli CC. An overview of benzene metabolism. Environ Health Perspect. 1996 Dec;104 Suppl 6:1165-71.
 Rana SV, Verma Y. Biochemical toxicity of benzene. J Environ Biol. 2005 Apr;26(2):157-68.
 Lanphear BP, Hornung R, ... Roberts R. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect. 2005 Jul;113(7):894-9.
 Canfield RL, Henderson CR Jr, ... Lanphear BP. Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter. N Engl J Med. 2003 Apr 17;348(16):1517-26.
 Schwartz J. Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environ Res. 1994 Apr;65(1):42-55.
 Wani AL, Ara A, Usmani JA. Lead toxicity: a review. Interdiscip Toxicol. 2015 Jun;8(2):55-64. doi: 10.1515/intox-2015-0009.
 Sokol RZ, Berman N. The effect of age of exposure on lead-induced testicular toxicity. Toxicology. 1991;69(3):269-78.
 Staudinger KC, Roth VS. Occupational lead poisoning. Am Fam Physician. 1998 Feb 15;57(4):719-26, 731-2.
 Sanborn MD, Abelsohn A, Campbell M, Weir E. Identifying and managing adverse environmental health effects: 3. Lead exposure. CMAJ. 2002 May 14;166(10):1287-92.
 Reuben A, Caspi A, ... Moffitt TE. Association of Childhood Blood Lead Levels With Cognitive Function and Socioeconomic Status at Age 38 Years and With IQ Change and Socioeconomic Mobility Between Childhood and Adulthood. JAMA. 2017 Mar 28;317(12):1244-1251. doi: 10.1001/jama.2017.1712.
 Liu J, Liu X, ... Dinges D. Early Blood Lead Levels and Sleep Disturbance in Preadolescence. Sleep. 2015 Dec 1;38(12):1869-74. doi: 10.5665/sleep.5230.
 Bouchard MF, Bellinger DC, ... Weisskopf MG. Blood lead levels and major depressive disorder, panic disorder, and generalized anxiety disorder in US young adults. Arch Gen Psychiatry. 2009 Dec;66(12):1313-9. doi: 10.1001/archgenpsychiatry.2009.164.
 Mudipalli A. Lead hepatotoxicity & potential health effects. Indian J Med Res. 2007 Dec;126(6):518-27.
 Flora G, Gupta D, Tiwari A. Toxicity of lead: A review with recent updates. Interdiscip Toxicol. 2012 Jun;5(2):47-58. doi: 10.2478/v10102-012-0009-2.
 Rastogi SK Renal effects of environmental and occupational lead exposure. Indian J Occup Environ Med. 2008 Dec;12(3):103-6. doi: 10.4103/0019-5278.44689
 Radosevic Z, Saric M, ... Knezevic J. The kidney in lead poisoning. Br J Ind Med. 1961 Jul;18:222-30.
 Ferreira de Mattos G, Costa C, ... Nicolson GL. Lead poisoning: acute exposure of the heart to lead ions promotes changes in cardiac function and Cav1.2 ion channels. Biophys Rev. 2017 Oct;9(5):807-825. doi: 10.1007/s12551-017-0303-5. Epub 2017 Aug 23.
 Navas-Acien A, Guallar E, Silbergeld EK, Rothenberg SJ. Lead exposure and cardiovascular disease--a systematic review. Environ Health Perspect. 2007 Mar;115(3):472-82. Epub 2006 Dec 22.
 Neal AP, Guilarte TR. Mechanisms of lead and manganese neurotoxicity. Toxicol Res (Camb). 2013 Mar 1;2(2):99-114.
 Sanders T, Liu Y, Buchner V, Tchounwou PB. Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health. 2009 Jan-Mar;24(1):15-45.
 Komarnicki GJ. Lead and cadmium in indoor air and the urban environment. Environ Pollut. 2005 Jul;136(1):47-61.
 Stewart-Pinkham SM. The effect of ambient cadmium air pollution on the hair mineral content of children. Sci Total Environ. 1989 Jan;78:289-96.
 Hyder O, Chung M,... Pawlik TM. Cadmium exposure and liver disease among US adults. J Gastrointest Surg. 2013 Jul;17(7):1265-73. doi: 10.1007/s11605-013-2210-9. Epub 2013 May 1.
 Kang MY, Cho SH, Lim YH, Seo JC, Hong YC. Effects of environmental cadmium exposure on liver function in adults. Occup Environ Med. 2013 Apr;70(4):268-73. doi: 10.1136/oemed-2012-101063. Epub 2013 Jan 15.
 Johri N, Jacquillet G, Unwin R. Heavy metal poisoning: the effects of cadmium on the kidney. Biometals. 2010 Oct;23(5):783-92. doi: 10.1007/s10534-010-9328-y. Epub 2010 Mar 31.
 Satarug S. Dietary Cadmium Intake and Its Effects on Kidneys. Toxics. 2018 Mar 10;6(1). pii: E15. doi: 10.3390/toxics6010015.
 Buser MC, Ingber SZ, ... Scinicariello F. Urinary and blood cadmium and lead and kidney function: NHANES 2007-2012. Int J Hyg Environ Health. 2016 May;219(3):261-7. doi: 10.1016/j.ijheh.2016.01.005. Epub 2016 Jan 28.
 Wallin M, Sallsten G, Lundh T, Barregard L. Low-level cadmium exposure and effects on kidney function. Occup Environ Med. 2014 Dec;71(12):848-54. doi: 10.1136/oemed-2014-102279. Epub 2014 Oct 6.
 Byber K, Lison D, ... Hotz P. Cadmium or cadmium compounds and chronic kidney disease in workers and the general population: a systematic review. Crit Rev Toxicol. 2016;46(3):191-240. doi: 10.3109/10408444.2015.1076375. Epub 2015 Oct 29.
 Minami A, Takeda A, ... Oku N. Cadmium toxicity in synaptic neurotransmission in the brain. Brain Res. 2001 Mar 16;894(2):336-9.
 Rinaldi M, Micali A, ... Minutoli L. Cadmium, Organ Toxicity and Therapeutic Approaches: A Review on Brain, Kidney and Testis Damage. Curr Med Chem. 2017 Nov 20;24(35):3879-3893. doi: 10.2174/0929867324666170801101448.
 Wang B, Du Y. Cadmium and its neurotoxic effects. Oxid Med Cell Longev. 2013;2013:898034. doi: 10.1155/2013/898034. Epub 2013 Aug 12.
 Benoff S, Jacob A, Hurley IR. Male infertility and environmental exposure to lead and cadmium. Hum Reprod Update. 2000 Mar-Apr;6(2):107-21.
 Pollack AZ, Ranasinghe S, Sjaarda LA, Mumford SL. Cadmium and Reproductive Health in Women: A Systematic Review of the Epidemiologic Evidence. Curr Environ Health Rep. 2014 Jun;1(2):172-184. Epub 2014 Mar 21.
 Paksy K, Varga B, Lázár P. Effect of cadmium on female fertility, pregnancy and postnatal development in the rat. Acta Physiol Hung. 1996;84(2):119-30.
 Benoff S, Hauser R, ... Centola GM. Cadmium concentrations in blood and seminal plasma: correlations with sperm number and motility in three male populations (infertility patients, artificial insemination donors, and unselected volunteers). Mol Med. 2009 Jul-Aug;15(7-8):248-62. doi: 10.2119/molmed.2008.00104.
 de Angelis C, Galdiero M, ... Pivonello R. The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility. Reprod Toxicol. 2017 Oct;73:105-127. doi: 10.1016/j.reprotox.2017.07.021. Epub 2017 Aug 1.
 Saksena SK, Lau IF. Effects of cadmium chloride on testicular steroidogenesis and fertility of male rats. Endokrinologie. 1979 Apr;74(1):6-12.
 Adamkovicova M, Toman R, ... Massanyi P. Sperm motility and morphology changes in rats exposed to cadmium and diazinon. Reprod Biol Endocrinol. 2016 Aug 8;14(1):42. doi: 10.1186/s12958-016-0177-6.
 Zhao X, Cheng Z, ... Luo Y. Effects of paternal cadmium exposure on the sperm quality of male rats and the neurobehavioral system of their offspring. Exp Ther Med. 2015 Dec;10(6):2356-2360. Epub 2015 Sep 25.
 Gennart JP, Buchet JP, ... Lauwerys R. Fertility of male workers exposed to cadmium, lead, or manganese. Am J Epidemiol. 1992 Jun 1;135(11):1208-19.
 Hartwig A. Cadmium and cancer. Met Ions Life Sci. 2013;11:491-507. doi: 10.1007/978-94-007-5179-8_15.
 Huff J, Lunn RM, Waalkes MP, Tomatis L, Infante PF. Cadmium-induced cancers in animals and in humans. Int J Occup Environ Health. 2007 Apr-Jun;13(2):202-12.
 García-Esquinas E, Pollan M, ... Navas-Acien A. Cadmium exposure and cancer mortality in a prospective cohort: the strong heart study. Environ Health Perspect. 2014 Apr;122(4):363-70. doi: 10.1289/ehp.1306587. Epub 2014 Feb 14.
 Chen C, Xun P, ... He K. Cadmium exposure and risk of prostate cancer: a meta-analysis of cohort and case-control studies among the general and occupational populations. Sci Rep. 2016 May 13;6:25814. doi: 10.1038/srep25814.
 Gallagher CM, Chen JJ, Kovach JS. Environmental cadmium and breast cancer risk. Aging (Albany NY). 2010 Nov;2(11):804-14.
 Mascagni P, Consonni D, ... Toffoletto F. Olfactory function in workers exposed to moderate airborne cadmium levels. Neurotoxicology. 2003 Aug;24(4-5):717-24.
 Bernard A. Cadmium & its adverse effects on human health. Indian J Med Res. 2008 Oct;128(4):557-64.
 Thun MJ, Osorio AM, ... Halperin W. Nephropathy in cadmium workers: assessment of risk from airborne occupational exposure to cadmium. Br J Ind Med. 1989 Oct;46(10):689-97.
 Lauwerys R, Bernard A,... Amery A. Does environmental exposure to cadmium represent a health risk? Conclusions from the Cadmibel study. Acta Clin Belg. 1991;46(4):219-25.
 Bonino S. Carbon Dioxide Detection and Indoor Air Quality Control. Occup Health Saf. 2016 Apr;85(4):46-8.
 Vehviläinen T, Lindholm H, ... Vinha J. High indoor CO2 concentrations in an office environment increases the transcutaneous CO2 level and sleepiness during cognitive work. J Occup Environ Hyg. 2016;13(1):19-29. doi: 10.1080/15459624.2015.1076160.
 Gaihre S, Semple S, ... Turner S. Classroom carbon dioxide concentration, school attendance, and educational attainment. J Sch Health. 2014 Sep;84(9):569-74. doi: 10.1111/josh.12183.
 Fromme H, Heitmann D, ... Twardella D. Air quality in schools - classroom levels of carbon dioxide (CO2), volatile organic compounds (VOC), aldehydes, endotoxins and cat allergen. Gesundheitswesen. 2008 Feb;70(2):88-97. doi: 10.1055/s-2008-1046775.
 Muscatiello N, McCarthy A, ... Lin S. Classroom conditions and CO2 concentrations and teacher health symptom reporting in 10 New York State Schools. Indoor Air. 2015 Apr;25(2):157-67. doi: 10.1111/ina.12136. Epub 2014 Jul 14.
 Tsai DH, Lin JS, Chan CC. Office workers' sick building syndrome and indoor carbon dioxide concentrations. J Occup Environ Hyg. 2012;9(5):345-51. doi: 10.1080/15459624.2012.675291.
 Lu CY, Lin JM, Chen YY, Chen YC. Building-Related Symptoms among Office Employees Associated with Indoor Carbon Dioxide and Total Volatile Organic Compounds. Int J Environ Res Public Health. 2015 May 27;12(6):5833-45. doi: 10.3390/ijerph120605833.
 Heebøll A, Wargocki P, Toftum J. Window and door opening behavior, carbon dioxide concentration, temperature, and energy use during the heating season in classrooms with different ventilation retrofits—ASHRAE RP1624. Science and Technology for the Built Environment 24(6) 2014.
 Satish U, Mendell MJ, ... Fisk WJ. Is CO2 an indoor pollutant? Direct effects of low-to-moderate CO2 concentrations on human decision-making performance. Environ Health Perspect. 2012 Dec;120(12):1671-7. doi: 10.1289/ehp.1104789. Epub 2012 Sep 20.
 Shendell DG, Prill R, ... Faulkner D. Associations between classroom CO2 concentrations and student attendance in Washington and Idaho. Indoor Air. 2004 Oct;14(5):333-41.
 Allen JG, MacNaughton P,... Spengler JD. Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments. Environ Health Perspect. 2016 Jun;124(6):805-12. doi: 10.1289/ehp.1510037. Epub 2015 Oct 26.
 Zhang X, Wargocki P, Lian Z, Thyregod C. Effects of exposure to carbon dioxide and bioeffluents on perceived air quality, self-assessed acute health symptoms, and cognitive performance. Indoor Air. 2017 Jan;27(1):47-64. doi: 10.1111/ina.12284. Epub 2016 Mar 7.
 Arlian LG, Neal JS, Vyszenski-Moher DL. Fluctuating hydrating and dehydrating relative humidities effects on the life cycle of Dermatophagoides farinae (Acari: Pyroglyphidae). J Med Entomol. 1999 Jul;36(4):457-61.
 Arlian LG, Alexander AK, ... Vyszenski-Moher DL. Reducing indoor humidity significantly reduces dust mites and allergen in homes. In: Proceedings of the European Academy of Allergy & Clinical Immunology Meeting, 2000.
 Vyszenski-Moher DL, Neal JS, ... Arlian LG. Maintaining low RH reduces dust mite and allergen levels in homes. Presented at the Entomological Society of America Meeting, 2000 Montreal.
 Vyszenski-Moher DL , Arlian LG, Neal JS. Effects of laundry detergents on Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Euroglyphus maynei. Ann Allergy Asthma Immunol. 2002 Jun;88(6):578-83.
 Arlian LG1, Neal JS, ... Alexander AK. Reducing relative humidity is a practical way to control dust mites and their allergens in homes in temperate climates. J Allergy Clin Immunol. 2001 Jan;107(1):99-104.
 Arlian LG, Neal JS, Vyszenski-Moher DL. Reducing relative humidity to control the house dust mite Dermatophagoides farinae. J Allergy Clin Immunol. 1999 Oct;104(4 Pt 1):852-6.
 Wang IJ, Tung TH, Tang CS, Zhao ZH. Allergens, air pollutants, and childhood allergic diseases. Int J Hyg Environ Health. 2016 Jan;219(1):66-71. doi: 10.1016/j.ijheh.2015.09.001. Epub 2015 Sep 18.
 Bartra J, Mullol J, ... Valero A. Air pollution and allergens. J Investig Allergol Clin Immunol. 2007;17 Suppl 2:3-8.
 Carrer P, Maroni M, Alcini D, Cavallo D. Allergens in indoor air: environmental assessment and health effects. Sci Total Environ. 2001 Apr 10;270(1-3):33-42.
 Castañeda AR, Vogel CFA, ... Pinkerton KE. Ambient particulate matter enhances the pulmonary allergic immune response to house dust mite in a BALB/c mouse model by augmenting Th2- and Th17-immune responses. Physiol Rep. 2018 Sep;6(18):e13827. doi: 10.14814/phy2.13827.
 Castañeda AR, Bein KJ, ... Pinkerton KE. Fine particulate matter (PM2.5) enhances allergic sensitization in BALB/c mice. J Toxicol Environ Health A. 2017;80(4):197-207. doi: 10.1080/15287394.2016.1222920. Epub 2017 May 11.
 Wu JZ, Ge DD, ... Li QY. Effects of particulate matter on allergic respiratory diseases. Chronic Dis Transl Med. 2018 Jun 8;4(2):95-102. doi: 10.1016/j.cdtm.2018.04.001. eCollection 2018 Jun.
 Erbas B, Jazayeri M, ... Dharmage SC. Outdoor pollen is a trigger of child and adolescent asthma emergency department presentations: A systematic review and meta-analysis. Allergy. 2018 Aug;73(8):1632-1641. doi: 10.1111/all.13407. Epub 2018 Mar 2.
 Jensen-Jarolim E, Pali-Schöll I, Kinaciyan T. Caution: Reptile pets shuttle grasshopper allergy and asthma into homes. World Allergy Organization Journal 2015 8:72.
 Dharmage SC, Lodge CL, Matheson MC, Campbell B, Lowe AJ. Exposure to cats: update on risks for sensitization and allergic diseases. Curr Allergy Asthma Rep. 2012 Oct;12(5):413-23. doi: 10.1007/s11882-012-0288-x.
 Konradsen JR, Nordlund B, ... Hedlin G. Severe childhood asthma and allergy to furry animals: Refined assessment using molecular‐based allergy diagnostics. Asthma in childhood 25(2).
 Burton OT, Oettgen HC. Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases. Immunol Rev. 2011 Jul;242(1):128-43. doi: 10.1111/j.1600-065X.2011.01024.x.
 Platts-Mills TA. The allergy epidemics: 1870-2010. J Allergy Clin Immunol. 2015 Jul;136(1):3-13. doi: 10.1016/j.jaci.2015.03.048.
 Braun-Fahrländer C, Lauener R. Farming and protective agents against allergy and asthma. Clin Exp Allergy. 2003 Apr;33(4):409-11.
 Ownby DR, Johnson CC, Peterson EL. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA. 2002 Aug 28;288(8):963-72.
 Lødrup Carlsen KC, Roll S, ... Keil T. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS One. 2012;7(8):e43214. doi: 10.1371/journal.pone.0043214. Epub 2012 Aug 29.
 Dunn RR, Fierer N, Henley JB, Leff JW, Menninger HL. Home life: factors structuring the bacterial diversity found within and between homes. PLoS One. 2013 May 22;8(5):e64133. doi: 10.1371/journal.pone.0064133. Print 2013.
 Yang MS, Lee SP, Kwon YJ, Lee SM. Dog and Cat Allergies and Allergen Avoidance Measures in Korean Adult Pet Owners Who Participated in a Pet Exhibition. Allergy Asthma Immunol Res. 2018 Mar;10(2):155-164. doi: 10.4168/aair.2018.10.2.155.
 Informed Health Online. Dust mite allergies: Overview. 2017.
 Miller JD. The Role of Dust Mites in Allergy. Clin Rev Allergy Immunol. 2018 Jun 23. doi: 10.1007/s12016-018-8693-0.
 Cinteza M, Daian C. House dust mite - the paradox. Maedica (Buchar). 2014 Dec;9(4):313-5.
 Kemp TJ, Siebers RW, ... Crane J. House dust mite allergen in pillows. BMJ. 1996 Oct 12;313(7062):916.
 Dryer AL, Chandler MJ, Hamilton RG. Dust-mite allergen removal from feathers by commercial processing. Ann Allergy Asthma Immunol. 2002 Jun;88(6):576-7.
 Vojta PJ, Randels SP,... Zeldin DC. Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban homes. Environ Health Perspect. 2001 Aug;109(8):815-9.
 Casley LS, Godec T, ... Dewhirst SY. How clean is your house? A study of house dust mites, allergens and other contents of dust samples collected from households. Int J Environ Health Res. 2018 Aug;28(4):341-357. doi: 10.1080/09603123.2018.1457141. Epub 2018 Jun 22.
 Ciprandi G, Puccinelli P, ... Italian Cometa Study Group. The relevance of house dust mites allergy in clinical practice: the epidemiological impact on allergen immunotherapy. Immunotherapy. 2017 Nov;9(15):1219-1224. doi: 10.2217/imt-2017-0086.
 Dzoro S, Mittermann I, ... Valenta R. House dust mites as potential carriers for IgE sensitization to bacterial antigens. Allergy. 2018 Jan;73(1):115-124. doi: 10.1111/all.13260. Epub 2017 Sep 7.
 Valmonte GR, Cauyan GA, Ramos JD. IgE cross-reactivity between house dust mite allergens and Ascaris lumbricoides antigens. Asia Pac Allergy. 2012 Jan;2(1):35-44. doi: 10.5415/apallergy.2012.2.1.35. Epub 2012 Jan 10.
 Wong L, Huang CH, Lee BW. Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin? Allergy Asthma Immunol Res. 2016 Mar;8(2):101-6. doi: 10.4168/aair.2016.8.2.101. Epub 2015 Jul 14.
 de Boer R, Kuller K. Mattresses as a winter refuge for house-dust mite populations. Allergy. 1997 Mar;52(3):299-305.
 Arruda LK, Vailes LD, ... Chapman MD. Cockroach allergens and asthma. J Allergy Clin Immunol. 2001 Mar;107(3):419-28.
 Sohn MH, Kim KE. The cockroach and allergic diseases. Allergy Asthma Immunol Res. 2012 Sep;4(5):264-9. doi: 10.4168/aair.2012.4.5.264. Epub 2012 May 22.
 Do DC, Zhao Y, Gao P. Cockroach allergen exposure and risk of asthma. Allergy. 2016 Apr;71(4):463-74. doi: 10.1111/all.12827. Epub 2016 Feb 4.
 Pomés A, Mueller GA, ... Arruda LK. New Insights into Cockroach Allergens. Curr Allergy Asthma Rep. 2017 Apr;17(4):25. doi: 10.1007/s11882-017-0694-1.
 Panzner P, Vachová M, ... Malý M. Cross-sectional study on sensitization to mite and cockroach allergen components in allergy patients in the Central European region. Clin Transl Allergy. 2018 Jun 4;8:19. doi: 10.1186/s13601-018-0207-x. eCollection 2018.
 Pomés A, Arruda LK. Investigating cockroach allergens: aiming to improve diagnosis and treatment of cockroach allergic patients. Methods. 2014 Mar 1;66(1):75-85. doi: 10.1016/j.ymeth.2013.07.036. Epub 2013 Aug 2.
 Zoratti EM, Krouse RZ, ... Liu AH. Asthma phenotypes in inner-city children. J Allergy Clin Immunol. 2016 Oct;138(4):1016-1029. doi: 10.1016/j.jaci.2016.06.061.
 Gergen PJ , Togias A. Inner city asthma. Immunol Allergy Clin North Am. 2015 Feb;35(1):101-14. doi: 10.1016/j.iac.2014.09.006. Epub 2014 Oct 18.
 Newell K, Kartsonaki C, Lam KBH, Kurmi O. Cardiorespiratory health effects of gaseous ambient air pollution exposure in low and middle income countries: a systematic review and meta-analysis. Environ Health. 2018 Apr 18;17(1):41. doi: 10.1186/s12940-018-0380-3.
 Zhao R, Chen S, ... Wei S. The impact of short-term exposure to air pollutants on the onset of out-of-hospital cardiac arrest: A systematic review and meta-analysis. Int J Cardiol. 2017 Jan 1;226:110-117. doi: 10.1016/j.ijcard.2016.10.053. Epub 2016 Oct 25.
 Song X, Liu Y, ... Wang S. Short-Term Exposure to Air Pollution and Cardiac Arrhythmia: A Meta-Analysis and Systematic Review. Int J Environ Res Public Health. 2016 Jun 28;13(7). pii: E642. doi: 10.3390/ijerph13070642.
 Uzoigwe JC, Prum T, Bresnahan E, Garelnabi M. The emerging role of outdoor and indoor air pollution in cardiovascular disease. N Am J Med Sci. 2013 Aug;5(8):445-53. doi: 10.4103/1947-2714.117290.
 Kan H, Wong CM, Vichit-Vadakan N, Qian Z; PAPA Project Teams. Short-term association between sulfur dioxide and daily mortality: the Public Health and Air Pollution in Asia (PAPA) study. Environ Res. 2010 Apr;110(3):258-64. doi: 10.1016/j.envres.2010.01.006. Epub 2010 Feb 1.
 Sunyer J, Atkinson R, ... APHEA 2 study. Respiratory effects of sulphur dioxide: a hierarchical multicity analysis in the APHEA 2 study. Occup Environ Med. 2003 Aug;60(8):e2.
 Lai HK, Tsang H, Wong CM. Meta-analysis of adverse health effects due to air pollution in Chinese populations. BMC Public Health. 2013 Apr 18;13:360. doi: 10.1186/1471-2458-13-360.
 Hehua Z, Qing C, Shanyan G, Qijun W, Yuhong Z. The impact of prenatal exposure to air pollution on childhood wheezing and asthma: A systematic review. Environ Res. 2017 Nov;159:519-530. doi: 10.1016/j.envres.2017.08.038. Epub 2017 Sep 8.
 Siddika N, Balogun HA, Amegah AK, Jaakkola JJ. Prenatal ambient air pollution exposure and the risk of stillbirth: systematic review and meta-analysis of the empirical evidence. Occup Environ Med. 2016 Sep;73(9):573-81. doi: 10.1136/oemed-2015-103086. Epub 2016 May 24.
 Jacobs M, Zhang G, ... Pereira G. The association between ambient air pollution and selected adverse pregnancy outcomes in China: A systematic review. Sci Total Environ. 2017 Feb 1;579:1179-1192. doi: 10.1016/j.scitotenv.2016.11.100. Epub 2016 Nov 29.
 Carré J, Gatimel N,... Léandri R. Does air pollution play a role in infertility?: a systematic review. Environ Health. 2017 Jul 28;16(1):82. doi: 10.1186/s12940-017-0291-8.
 Shah PS, Balkhair T; Knowledge Synthesis Group on Determinants of Preterm/LBW births. Air pollution and birth outcomes: a systematic review. Environ Int. 2011 Feb;37(2):498-516. doi: 10.1016/j.envint.2010.10.009. Epub 2010 Nov 26.
 Woodford DM, Coutu RE, Gaensler EA. Obstructive lung disease from acute sulfur dioxide exposure. Respiration. 1979;38(4):238-45.
 Osterman JW, Greaves IA, ... Thériault G. Respiratory symptoms associated with low level sulphur dioxide exposure in silicon carbide production workers. Br J Ind Med. 1989 Sep;46(9):629-35.
 Li X, Yi H, Wang H. Sulphur dioxide and arsenic affect male reproduction via interfering with spermatogenesis in mice. Ecotoxicol Environ Saf. 2018 Dec 15;165:164-173. doi: 10.1016/j.ecoenv.2018.08.109. Epub 2018 Sep 5.
 Zhang J, Zheng F, ... Wang J. Sulfur dioxide inhalation lowers sperm quality and alters testicular histology via increasing expression of CREM and ACT proteins in rat testes. Environ Toxicol Pharmacol. 2016 Oct;47:47-52. doi: 10.1016/j.etap.2016.09.001. Epub 2016 Sep 4.
 Meng Z, Bai W. Oxidation damage of sulfur dioxide on testicles of mice. Environ Res. 2004 Nov;96(3):298-304.
 An JL, Wang YS, Li X, Sun Y, Shen SH. Relationship between surface UV radiation and air pollution in Beijing. Huan Jing Ke Xue. 2008 Apr;29(4):1053-8.
 Hoseinzadeh E, Taha P, ... Miri M. The impact of air pollutants, UV exposure and geographic location on vitamin D deficiency. Food Chem Toxicol. 2018 Mar;113:241-254. doi: 10.1016/j.fct.2018.01.052. Epub 2018 Feb 1.
 Liu J, Zhang W. The influence of the environment and clothing on human exposure to ultraviolet light. PLoS One. 2015 Apr 29;10(4):e0124758. doi: 10.1371/journal.pone.0124758. eCollection 2015.
 Barrea L, Savastano S, ... Colao A. Low serum vitamin D-status, air pollution and obesity: A dangerous liaison. Rev Endocr Metab Disord. 2017 Jun;18(2):207-214. doi: 10.1007/s11154-016-9388-6.
 Hosseinpanah F, Pour SH, ... Azizi F. The effects of air pollution on vitamin D status in healthy women: a cross sectional study. BMC Public Health. 2010 Aug 29;10:519. doi: 10.1186/1471-2458-10-519.
 Siddens LK, Larkin A, ...Baird WM. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol. 2012 Nov 1;264(3):377-86. doi: 10.1016/j.taap.2012.08.014. Epub 2012 Aug 23.
 Satarug S, Moore MR. Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke. Environ Health Perspect. 2004 Jul;112(10):1099-103.
 Nawrot T, Plusquin M, ... Staessen JA. Environmental exposure to cadmium and risk of cancer: a prospective population-based study. Lancet Oncol. 2006 Feb;7(2):119-26.
 Exercise and air quality: 10 top tips. Breathe (Sheff). 2015 Sep;11(3):239-42. doi: 10.1183/20734735.ELF113.
 WHO Europe. Review of evidence on health aspects of air pollution – REVIHAAP Project: Technical Report. Proximity to roads, NO2, other air pollutants and their mixtures
 Barnes NM, Ng TW, Ma KK, Lai KM. In-Cabin Air Quality during Driving and Engine Idling in Air-Conditioned Private Vehicles in Hong Kong. Int J Environ Res Public Health. 2018 Mar 27;15(4). pii: E611. doi: 10.3390/ijerph15040611.
 Zhang K, Batterman S. Air pollution and health risks due to vehicle traffic. Sci Total Environ. 2013 Apr 15;450-451:307-16. doi: 10.1016/j.scitotenv.2013.01.074.
 Moreno T, Reche C, ... Gibbons W. Urban air quality comparison for bus, tram, subway and pedestrian commutes in Barcelona. Environ Res. 2015 Oct;142:495-510. doi: 10.1016/j.envres.2015.07.022. Epub 2015 Aug 13.
 Chaney RA, Sloan CD, ... Johnston JD. Personal exposure to fine particulate air pollution while commuting: An examination of six transport modes on an urban arterial roadway. PLoS One. 2017 Nov 9;12(11):e0188053. doi: 10.1371/journal.pone.0188053. eCollection 2017.
 Weng M, Jin X. Study on the air pollution in typical transportation microenvironment: Characteristics and health risks. J Air Waste Manag Assoc. 2015 Jan;65(1):59-63. doi: 10.1080/10962247.2014.962648.
 Nasir ZA, Colbeck I. Particulate air pollution in transport micro-environments. J Environ Monit. 2009 Jun;11(6):1140-6. doi: 10.1039/b821824b. Epub 2009 Apr 8.
 Riediker M. Cardiovascular effects of fine particulate matter components in highway patrol officers. Inhal Toxicol. 2007;19 Suppl 1:99-105.
 Riediker M, Devlin RB, ... Cascio WE. Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissions. Part Fibre Toxicol. 2004 Dec 9;1(1):2.
 Barrea L, Savastano S, ... Colao A. Low serum vitamin D-status, air pollution and obesity: A dangerous liaison. Rev Endocr Metab Disord. 2017 Jun;18(2):207-214. doi: 10.1007/s11154-016-9388-6.
 Liu J, Zhang W. The influence of the environment and clothing on human exposure to ultraviolet light. PLoS One. 2015 Apr 29;10(4):e0124758. doi: 10.1371/journal.pone.0124758. eCollection 2015.
 Hoseinzadeh E, Taha P, ... Miri M. The impact of air pollutants, UV exposure and geographic location on vitamin D deficiency. Food Chem Toxicol. 2018 Mar;113:241-254. doi: 10.1016/j.fct.2018.01.052. Epub 2018 Feb 1.
 An JL, Wang YS, Li X, Sun Y, Shen SH. Relationship between surface UV radiation and air pollution in Beijing. Huan Jing Ke Xue. 2008 Apr;29(4):1053-8.
 Ng TP, Seet CS, Tan WC, Foo SC. Nitrogen dioxide exposure from domestic gas cooking and airway response in asthmatic women. Thorax. 2001 Aug;56(8):596-601.
 Nicole W. Cooking up indoor air pollution: emissions from natural gas stoves. Environ Health Perspect. 2014 Jan;122(1):A27. doi: 10.1289/ehp.122-A27.
 Eisner MD, Blanc PD. Gas stove use and respiratory health among adults with asthma in NHANES III. Occup Environ Med. 2003 Oct;60(10):759-64.
 Luczynska CM, Li Y, Chapman MD, Platts-Mills TA. Airborne concentrations and particle size distribution of allergen derived from domestic cats (Felis domesticus). Measurements using cascade impactor, liquid impinger, and a two-site monoclonal antibody assay for Fel d I. m Rev Respir Dis. 1990 Feb;141(2):361-7.
 Péter S, Holguin F, ... Eggersdorfer M. Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution. Nutrients. 2015 Dec 10;7(12):10398-416. doi: 10.3390/nu7125539.
 Romieu I, Téllez-Rojo MM, ... Holguin F. Omega-3 fatty acid prevents heart rate variability reductions associated with particulate matter. Am J Respir Crit Care Med. 2005 Dec 15;172(12):1534-40. Epub 2005 Oct 6.
 Romieu I, Castro-Giner F, Kunzli N, Sunyer J. Air pollution, oxidative stress and dietary supplementation: a review. Eur Respir J. 2008 Jan;31(1):179-97. doi: 10.1183/09031936.00128106.
 Hennig B, Ettinger AS, ... Suk WA. Using nutrition for intervention and prevention against environmental chemical toxicity and associated diseases. Environ Health Perspect. 2007 Apr;115(4):493-5. Epub 2007 Jan 16.
 Whyand T, Hurst JR, Beckles M, Caplin ME. Pollution and respiratory disease: can diet or supplements help? A review. Respir Res. 2018 May 2;19(1):79. doi: 10.1186/s12931-018-0785-0.
 Ou CQ, Wong CM, ... Lam TH. Dietary habits and the short-term effects of air pollution on mortality in the Chinese population in Hong Kong. J Epidemiol Community Health. 2012 Mar;66(3):254-8. doi: 10.1136/jech.2009.103275. Epub 2010 Sep 30.
 Schulz AJ, Mentz GB, ... Izumi B. Effects of particulate matter and antioxidant dietary intake on blood pressure. Am J Public Health. 2015 Jun;105(6):1254-61. doi: 10.2105/AJPH.2014.302176. Epub 2014 Oct 16.
 Kelly FJ, Fussell JC. Linking ambient particulate matter pollution effects with oxidative biology and immune responses. Ann N Y Acad Sci. 2015 Mar;1340:84-94. doi: 10.1111/nyas.12720. Epub 2015 Feb 25.
 Nel AE, Diaz-Sanchez D, Li N. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr Opin Pulm Med. 2001 Jan;7(1):20-6.
 Peters A, von Klot S,... Cooperative Health Research in the Region of Augsburg Study Group. Exposure to traffic and the onset of myocardial infarction. N Engl J Med. 2004 Oct 21;351(17):1721-30.
 Poljšak B, Fink R. The protective role of antioxidants in the defence against ROS/RNS-mediated environmental pollution. Oxid Med Cell Longev. 2014;2014:671539. doi: 10.1155/2014/671539. Epub 2014 Jul 20.
 Romieu I, Garcia-Esteban R, ... Holguin F. The effect of supplementation with omega-3 polyunsaturated fatty acids on markers of oxidative stress in elderly exposed to PM(2.5). Environ Health Perspect. 2008 Sep;116(9):1237-42. doi: 10.1289/ehp.10578.
 Kelly FJ. Dietary antioxidants and environmental stress. Proc Nutr Soc. 2004 Nov;63(4):579-85.
 Tong H, Rappold AG, ... Samet JM. Omega-3 fatty acid supplementation appears to attenuate particulate air pollution-induced cardiac effects and lipid changes in healthy middle-aged adults. Environ Health Perspect. 2012 Jul;120(7):952-7. doi: 10.1289/ehp.1104472. Epub 2012 Apr 19.
 Baccarelli A, Cassano PA, ... Schwartz J. Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms. Circulation. 2008 Apr 8;117(14):1802-9. doi: 10.1161/CIRCULATIONAHA.107.726067. Epub 2008 Mar 31.
 Heber D, Li Z, Garcia-Lloret M, ... Zhang Y, Nel A. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014 Jan;5(1):35-41. doi: 10.1039/c3fo60277j.
 Egner PA, Chen JG, ... Kensler TW. Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China. Cancer Prev Res (Phila). 2014 Aug;7(8):813-823. doi: 10.1158/1940-6207.CAPR-14-0103. Epub 2014 Jun 9.
 Manicourt DH, Devogelaer JP. Urban tropospheric ozone increases the prevalence of vitamin D deficiency among Belgian postmenopausal women with outdoor activities during summer. J Clin Endocrinol Metab. 2008 Oct;93(10):3893-9. doi: 10.1210/jc.2007-2663. Epub 2008 Jul 15.
 Agarwal KS, Mughal MZ, ... Puliyel JM. The impact of atmospheric pollution on vitamin D status of infants and toddlers in Delhi, India. Arch Dis Child. 2002 Aug;87(2):111-3.
 Hosseinpanah F, Pour SH, ... Azizi F. The effects of air pollution on vitamin D status in healthy women: a cross sectional study. BMC Public Health. 2010 Aug 29;10:519. doi: 10.1186/1471-2458-10-519.
 Macintosh DL, Minegishi T, ... Myatt TA. The benefits of whole-house in-duct air cleaning in reducing exposures to fine particulate matter of outdoor origin: a modeling analysis. J Expo Sci Environ Epidemiol. 2010 Mar;20(2):213-24. doi: 10.1038/jes.2009.16. Epub 2009 Mar 25.
 Lovett-Racke AE, Racke MK. Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells. Cell Immunol. 2002 Jan;215(1):54-60.
 Mancebo SE, Wang SQ. Recognizing the impact of ambient air pollution on skin health. J Eur Acad Dermatol Venereol. 2015 Dec;29(12):2326-32. doi: 10.1111/jdv.13250. Epub 2015 Aug 20.
 Vierkötter A, Schikowski T, ...Krutmann J. Airborne particle exposure and extrinsic skin aging. J Invest Dermatol. 2010 Dec;130(12):2719-26. doi: 10.1038/jid.2010.204. Epub 2010 Jul 22.
 Meng QY, Spector D, Colome S, Turpin B. Determinants of Indoor and Personal Exposure to PM(2.5) of Indoor and Outdoor Origin during the RIOPA Study. Atmos Environ (1994). 2009 Nov;43(36):5750-5758.
 Huang YL, Chen HW, ... Chuang KJ. Personal exposure to household particulate matter, household activities and heart rate variability among housewives. PLoS One. 2014 Mar 3;9(3):e89969. doi: 10.1371/journal.pone.0089969. eCollection 2014.
 Macintosh DL, Myatt TA ... Spengler JD. Whole house particle removal and clean air delivery rates for in-duct and portable ventilation systems. J Air Waste Manag Assoc. 2008 Nov;58(11):1474-82.
 Macintosh DL, Minegishi T, ... Myatt TA. The benefits of whole-house in-duct air cleaning in reducing exposures to fine particulate matter of outdoor origin: a modeling analysis. J Expo Sci Environ Epidemiol. 2010 Mar;20(2):213-24. doi: 10.1038/jes.2009.16. Epub 2009 Mar 25.
 Daigle CC, Chalupa DC, ... Frampton MW. Ultrafine particle deposition in humans during rest and exercise. Inhal Toxicol. 2003 May;15(6):539-52.
 Bennett WD, Zeman KL, Jarabek AM. Nasal contribution to breathing and fine particle deposition in children versus adults. J Toxicol Environ Health A. 2008;71(3):227-37.
 Campbell ME, Li Q, ... Cheng S. Should people be physically active outdoors on smog alert days? Can J Public Health. 2005 Jan-Feb;96(1):24-8.
 Warburton DE, Nicol CW, Bredin S. Health benefits of physical activity: the evidence. CMAJ. 2006 Mar 14;174(6):801-9.
 Hartog JJ, Boogaard H, Nijland H, Hoek G. Do the health benefits of cycling outweigh the risks? Cien Saude Colet. 2011 Dec;16(12):4731-44.
 Rojas-Rueda D, de Nazelle A, Teixidó O, Nieuwenhuijsen MJ. Replacing car trips by increasing bike and public transport in the greater Barcelona metropolitan area: a health impact assessment study. Environ Int. 2012 Nov 15;49:100-9. doi: 10.1016/j.envint.2012.08.009. Epub 2012 Sep 21.
 Tainio M, de Nazelle AJ, ... Woodcock J. Can air pollution negate the health benefits of cycling and walking? Prev Med. 2016 Jun;87:233-236. doi: 10.1016/j.ypmed.2016.02.002. Epub 2016 May 5.
 Zuurbier M, Hoek G, ... Brunekreef B. Commuters' exposure to particulate matter air pollution is affected by mode of transport, fuel type, and route. Environ Health Perspect. 2010 Jun;118(6):783-9. doi: 10.1289/ehp.0901622. Epub 2010 Feb 25.
 Hudda N, Kostenidou E, Sioutas C, Delfino RJ, Fruin SA. Vehicle and driving characteristics that influence in-cabin particle number concentrations. Environ Sci Technol. 2011 Oct 15;45(20):8691-7. doi: 10.1021/es202025m. Epub 2011 Sep 19.
 Langrish JP, Mills NL ... Jiang L. Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. Part Fibre Toxicol. 2009 Mar 13;6:8. doi: 10.1186/1743-8977-6-8.
 Langrish JP, Li X, Wang S, ... Jiang L. Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease. Environ Health Perspect. 2012 Mar;120(3):367-72. doi: 10.1289/ehp.1103898.
 Jones JG. The physiological cost of wearing a disposable respirator. Am Ind Hyg Assoc J. 1991 Jun;52(6):219-25.
 Hussain S, Laumbach R, ... Kipen H. Controlled exposure to diesel exhaust causes increased nitrite in exhaled breath condensate among subjects with asthma. J Occup Environ Med. 2012 Oct;54(10):1186-91. doi: 10.1097/JOM.0b013e31826bb64c
 Wright RJ, Brunst KJ. Programming of respiratory health in childhood: influence of outdoor air pollution. v
 Backes CH, Nelin T, Gorr MW, Wold LE. Early life exposure to air pollution: how bad is it? Toxicol Lett. 2013 Jan 10;216(1):47-53. doi: 10.1016/j.toxlet.2012.11.007. Epub 2012 Nov 16.
 Bell ML, Zanobetti A, Dominici F. Evidence on vulnerability and susceptibility to health risks associated with short-term exposure to particulate matter: a systematic review and meta-analysis. Am J Epidemiol. 2013 Sep 15;178(6):865-76. doi: 10.1093/aje/kwt090. Epub 2013 Jul 25.
 Chen Z, Salam MT, .... Gilliland FD. Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study. J Thorac Dis. 2015 Jan;7(1):46-58. doi: 10.3978/j.issn.2072-1439.2014.12.20.
 Brook RD, Rajagopalan S, ... Kaufman JD. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation. 2010 Jun 1;121(21):2331-78. doi: 10.1161/CIR.0b013e3181dbece1. Epub 2010 May 10.
 Klingberg J, Broberg M, ... Pleijel H. Influence of urban vegetation on air pollution and noise exposure - A case study in Gothenburg, Sweden. Sci Total Environ. 2017 Dec 1;599-600:1728-1739. doi: 10.1016/j.scitotenv.2017.05.051. Epub 2017 May 20.
 Setälä H, Viippola V, ... Yli-Pelkonen V. Does urban vegetation mitigate air pollution in northern conditions? Environ Pollut. 2013 Dec;183:104-12. doi: 10.1016/j.envpol.2012.11.010. Epub 2012 Dec 27.
 Vos PE, Maiheu B, Vankerkom J, Janssen S. Improving local air quality in cities: to tree or not to tree? Environ Pollut. 2013 Dec;183:113-22. doi: 10.1016/j.envpol.2012.10.021. Epub 2012 Nov 27.
 Gourdji S. Review of plants to mitigate particulate matter, ozone as well as nitrogen dioxide air pollutants and applicable recommendations for green roofs in Montreal, Quebec. Environ Pollut. 2018 Oct;241:378-387. doi: 10.1016/j.envpol.2018.05.053. Epub 2018 May 28.
 Przybysz A, Sæbø A, Hanslin HM, Gawroński SW. Accumulation of particulate matter and trace elements on vegetation as affected by pollution level, rainfall and the passage of time. Sci Total Environ. 2014 May 15;481:360-9. doi: 10.1016/j.scitotenv.2014.02.072. Epub 2014 Mar 7.
 Wang H, Shi H, Wang Y. Effects of weather, time, and pollution level on the amount of particulate matter deposited on leaves of Ligustrum lucidum. ScientificWorldJournal. 2015;2015:935942. doi: 10.1155/2015/935942. Epub 2015 Jan 1.
 Sæbø A, Popek R, ... Gawronski SW. Plant species differences in particulate matter accumulation on leaf surfaces. Sci Total Environ. 2012 Jun 15;427-428:347-54. doi: 10.1016/j.scitotenv.2012.03.084. Epub 2012 May 2.
 Liang D, Ma C, Wang YQ, Wang YJ, Chen-Xi Z. Quantifying PM2.5 capture capability of greening trees based on leaf factors analyzing. Environ Sci Pollut Res Int. 2016 Nov;23(21):21176-21186. Epub 2016 Sep 19.
 Nguyen T, Yu X, Zhang Z, Liu M, Liu X. Relationship between types of urban forest and PM2.5 capture at three growth stages of leaves. J Environ Sci (China). 2015 Jan 1;27:33-41. doi: 10.1016/j.jes.2014.04.019. Epub 2014 Dec 3.
 Weerakkody U, Dover JW, Mitchell P, Reiling K. Quantification of the traffic-generated particulate matter capture by plant species in a living wall and evaluation of the important leaf characteristics. Sci Total Environ. 2018 Sep 1;635:1012-1024. doi: 10.1016/j.scitotenv.2018.04.106. Epub 2018 Apr 24.
 Mo L, Ma Z, ... Yu X. Assessing the Capacity of Plant Species to Accumulate Particulate Matter in Beijing, China. PLoS One. 2015 Oct 27;10(10):e0140664. doi: 10.1371/journal.pone.0140664. eCollection 2015.
 Chen J, Yu X, Bi H, Fu Y. Indoor simulations reveal differences among plant species in capturing particulate matter. PLoS One. 2017 May 16;12(5):e0177539. doi: 10.1371/journal.pone.0177539. eCollection 2017.
 Zhang T, Bai Y, Hong X, Sun L, Liu Y. Particulate matter and heavy metal deposition on the leaves of Euonymus japonicus during the East Asian monsoon in Beijing, China. PLoS One. 2017 Jun 29;12(6):e0179840. doi: 10.1371/journal.pone.0179840. eCollection 2017.
 Neu J, Rushing J. Cesarean versus vaginal delivery: long-term infant outcomes and the hygiene hypothesis. Clin Perinatol. 2011 Jun;38(2):321-31. doi: 10.1016/j.clp.2011.03.008.
 Mueller NT, Bakacs E, ... Dominguez-Bello MG. The infant microbiome development: mom matters. Trends Mol Med. 2015 Feb;21(2):109-17. doi: 10.1016/j.molmed.2014.12.002. Epub 2014 Dec 11.
 Strachan DP. Family size, infection and atopy: the first decade of the "hygiene hypothesis". Thorax. 2000 Aug;55 Suppl 1:S2-10.
 van Neerven RJ, Knol EF, Heck JM, Savelkoul HF. Which factors in raw cow's milk contribute to protection against allergies? J Allergy Clin Immunol. 2012 Oct;130(4):853-8. doi: 10.1016/j.jaci.2012.06.050. Epub 2012 Aug 30.
 Hodgkinson AJ, McDonald NA, Hine B. Effect of raw milk on allergic responses in a murine model of gastrointestinal allergy. Br J Nutr. 2014 Aug 14;112(3):390-7. doi: 10.1017/S0007114514001044. Epub 2014 May 29.
 Wolfe ND, Dunavan CP, Diamond J. Origins of major human infectious diseases. Nature. 2007 May 17;447(7142):279-83.
 Sironi M, Clerici M. The hygiene hypothesis: an evolutionary perspective. Microbes Infect. 2010 Jun;12(6):421-7. doi: 10.1016/j.micinf.2010.02.002. Epub 2010 Feb 21.
 Zock JP1, Plana E, ... Kogevinas M. The use of household cleaning sprays and adult asthma: an international longitudinal study. Am J Respir Crit Care Med. 2007 Oct 15;176(8):735-41. Epub 2007 Jun 21.
 Gibson PG, Henry RL, ... Wang H. Migration to a western country increases asthma symptoms but not eosinophilic airway inflammation. Pediatr Pulmonol. 2003 Sep;36(3):209-15.
 Wolkoff P. Indoor air humidity, air quality, and health - An overview. Int J Hyg Environ Health. 2018 Apr;221(3):376-390. doi: 10.1016/j.ijheh.2018.01.015. Epub 2018 Jan 31.
 Arundel AV, Sterling EM, Biggin JH, Sterling TD. Indirect health effects of relative humidity in indoor environments. Environ Health Perspect. 1986 Mar;65:351-61.
 Fang L, Clausen G, Fanger PO. Impact of temperature and humidity on chemical and sensory emissions from building materials. Indoor Air. 1999 Sep;9(3):193-201.
 Wolkoff P, Kjaergaard SK. The dichotomy of relative humidity on indoor air quality. Environ Int. 2007 Aug;33(6):850-7. Epub 2007 May 17.
 Bluyssen PM, Roda C,... Bartzis J. Self-reported health and comfort in 'modern' office buildings: first results from the European OFFICAIR study. Indoor Air. 2016 Apr;26(2):298-317. doi: 10.1111/ina.12196. Epub 2015 Mar 14.
 Brightman HS, Milton DK, ... Spengler JD. Evaluating building-related symptoms using the US EPA BASE study results. Indoor Air. 2008 Aug;18(4):335-45. doi: 10.1111/j.1600-0668.2008.00557.x.
 Angelon-Gaetz KA, Richardson DB, Marshall SW, Hernandez ML. Exploration of the effects of classroom humidity levels on teachers' respiratory symptoms. Int Arch Occup Environ Health. 2016 Jul;89(5):729-37. doi: 10.1007/s00420-016-1111-0. Epub 2016 Jan 27.
 Azuma K, Ikeda K, Kagi N, Yanagi U, Osawa H. Prevalence and risk factors associated with nonspecific building-related symptoms in office employees in Japan: relationships between work environment, Indoor Air Quality, and occupational stress. Indoor Air. 2015 Oct;25(5):499-511. doi: 10.1111/ina.12158. Epub 2014 Oct 24.
 Azuma K, Ikeda K, Kagi N, Yanagi U, Osawa H. Evaluating prevalence and risk factors of building-related symptoms among office workers: Seasonal characteristics of symptoms and psychosocial and physical environmental factors. Environ Health Prev Med. 2017 Apr 12;22(1):38. doi: 10.1186/s12199-017-0645-4.
 Lukcso D, Guidotti TL, Franklin DE, Burt A. Indoor environmental and air quality characteristics, building-related health symptoms, and worker productivity in a federal government building complex. Arch Environ Occup Health. 2016;71(2):85-101. doi: 10.1080/19338244.2014.965246. Epub 2014 Sep 25.
 Reinikainen LM, Jaakkola JJ. Significance of humidity and temperature on skin and upper airway symptoms. Indoor Air. 2003 Dec;13(4):344-52.
 Markowicz P, Larsson L. Influence of relative humidity on VOC concentrations in indoor air. Environ Sci Pollut Res Int. 2015 Apr;22(8):5772-9. doi: 10.1007/s11356-014-3678-x. Epub 2014 Oct 28.
 Huang S, Xiong J, Cai C, Xu W, Zhang Y. Influence of humidity on the initial emittable concentration of formaldehyde and hexaldehyde in building materials: experimental observation and correlation. Sci Rep. 2016 Mar 30;6:23388. doi: 10.1038/srep23388.
 Kang J, Liu J, Pei J. The indoor volatile organic compound (VOC) characteristics and source identification in a new university campus in Tianjin, China. J Air Waste Manag Assoc. 2017 Jun;67(6):725-737. doi: 10.1080/10962247.2017.1280561. Epub 2017 Feb 2.
 Chin JY, Godwin C,... Batterman S. Levels and sources of volatile organic compounds in homes of children with asthma. Indoor Air. 2014 Aug;24(4):403-15. doi: 10.1111/ina.12086. Epub 2014 Jan 13.
 McDonald BC, de Gouw JA, ... Trainer M. Volatile chemical products emerging as largest petrochemical source of urban organic emissions. Science. 2018 Feb 16;359(6377):760-764. doi: 10.1126/science.aaq0524.
 Potera C. Scented products emit a bouquet of VOCs. Environ Health Perspect. 2011 Jan;119(1):A16. doi: 10.1289/ehp.119-a16.
 LeBouf RF, Virji MA, ... Stefaniak AB. Exposure to volatile organic compounds in healthcare settings. Occup Environ Med. 2014 Sep;71(9):642-50. doi: 10.1136/oemed-2014-102080. Epub 2014 Jul 10.
 An JY, Kim S, Kim HJ. Formaldehyde and TVOC emission behavior of laminate flooring by structure of laminate flooring and heating condition. J Hazard Mater. 2011 Mar 15;187(1-3):44-51. doi: 10.1016/j.jhazmat.2010.08.086. Epub 2010 Aug 27.
 Hong SH, Hong J, Yu J, Lim Y. Study of the removal difference in indoor particulate matter and volatile organic compounds through the application of plants. Environ Health Toxicol. 2017 Feb 22;32:e2017006. doi: 10.5620/eht.e2017006. eCollection 2017.
 Dela Cruz M, Christensen JH, Thomsen JD, Müller R. Can ornamental potted plants remove volatile organic compounds from indoor air? A review. Environ Sci Pollut Res Int. 2014 Dec;21(24):13909-28. doi: 10.1007/s11356-014-3240-x. Epub 2014 Jul 25.
 Papinchak HL, Holcomb EJ, ... Decoteau DR. Effectiveness of Houseplants in Reducing the Indoor Air Pollutant Ozone. HortTechnology 2009 19(2): 286-290.
 Orwell RL, Wood RL, ... Burchett MD. Removal of Benzene by the Indoor Plant/Substrate Microcosm and Implications for Air Quality. Water, Air, and Soil Pollution 2004 157 (1–4): 193–207.
 Kim HH, Yang JY, ... Lim YW. House-plant placement for indoor air purification and health benefits on asthmatics. Environ Health Toxicol. 2014 Oct 8;29:e2014014. doi: 10.5620/eht.e2014014. eCollection 2014.
 Gawrońska H, Bakera B. Phytoremediation of particulate matter from indoor air by Chlorophytum comosum L. plants. Air Qual Atmos Health. 2015;8(3):265-272. Epub 2014 Aug 9.
 Brilli F, Fares S, ... Menghini F. Plants for Sustainable Improvement of Indoor Air Quality. Trends Plant Sci. 2018 Jun;23(6):507-512. doi: 10.1016/j.tplants.2018.03.004. Epub 2018 Apr 19.
 Yang DS, Pennisi SV, ... Kays SJ. Screening indoor plants for volatile organic pollutant removal efficiency. HortScience August 2009 44(5): 1377-1381.
 Xu Z, Wang L, Hou H. Formaldehyde removal by potted plant-soil systems. J Hazard Mater. 2011 Aug 15;192(1):314-8. doi: 10.1016/j.jhazmat.2011.05.020. Epub 2011 May 17.
 Feng Q, Zhang H, Dong Z, Zhou Y, Ma J. Circulating 25-hydroxyvitamin D and lung cancer risk and survival: A dose-response meta-analysis of prospective cohort studies. Medicine (Baltimore). 2017 Nov;96(45):e8613. doi: 10.1097/MD.0000000000008613.
 Liu J, Dong Y, ... Zhao Q. Meta-analysis of the correlation between vitamin D and lung cancer risk and outcomes. Oncotarget. 2017 Jun 28;8(46):81040-81051. doi: 10.18632/oncotarget.18766. eCollection 2017 Oct 6.
 Martineau AR, Cates CJ, ... Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev. 2016 Sep 5;9:CD011511. doi: 10.1002/14651858.CD011511.pub2.
 Brehm JM, Schuemann B, ... Childhood Asthma Management Program Research Group. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol. 2010 Jul;126(1):52-8.e5. doi: 10.1016/j.jaci.2010.03.043. Epub 2010 Jun 9.
 Gupta A, Sjoukes A, ... Saglani S. Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med. 2011 Dec 15;184(12):1342-9. doi: 10.1164/rccm.201107-1239OC. Epub 2011 Sep 8.
 Bourdrel T, Bind MA, ... Argacha JF. Cardiovascular effects of air pollution. Arch Cardiovasc Dis. 2017 Nov;110(11):634-642. doi: 10.1016/j.acvd.2017.05.003. Epub 2017 Jul 21.
 Rennolds J, Malireddy S, ... Cormet-Boyaka E. Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium. Biochem Biophys Res Commun. 2012 Jan 6;417(1):256-61. doi: 10.1016/j.bbrc.2011.11.096. Epub 2011 Nov 28.
 Ng TP, Niti M, ... Tan WC. Curcumins-rich curry diet and pulmonary function in Asian older adults. PLoS One. 2012;7(12):e51753. doi: 10.1371/journal.pone.0051753. Epub 2012 Dec 26.
 Panahi Y, Ghanei M, Hajhashemi A, Sahebkar A. Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial. J Diet Suppl. 2016;13(1):93-105. doi: 10.3109/19390211.2014.952865. Epub 2014 Aug 29.
 Snow SJ, Cheng WY, ... Kodavanti UP. Ozone-Induced Vascular Contractility and Pulmonary Injury Are Differentially Impacted by Diets Enriched With Coconut Oil, Fish Oil, and Olive Oil. Toxicol Sci. 2018 May 1;163(1):57-69. doi: 10.1093/toxsci/kfy003.
 Romieu I, Barraza-Villarreal A, ... Del Rio-Navarro BE. Dietary intake, lung function and airway inflammation in Mexico City school children exposed to air pollutants. Respir Res. 2009 Dec 10;10:122. doi: 10.1186/1465-9921-10-122.
 Mehta AK, Singh BP, Arora N, Gaur SN. Choline attenuates immune inflammation and suppresses oxidative stress in patients with asthma. Immunobiology. 2010 Jul;215(7):527-34. doi: 10.1016/j.imbio.2009.09.004. Epub 2009 Nov 7.
 Detopoulou P, Panagiotakos DB, ... Stefanadis C. Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study. Am J Clin Nutr. 2008 Feb;87(2):424-30.
 Orecchio S, Fiore M, ... Vara G. Volatile Profiles of Emissions from Different Activities Analyzed Using Canister Samplers and Gas Chromatography-Mass Spectrometry (GC/MS) Analysis: A Case Study. Int J Environ Res Public Health. 2017 Feb 15;14(2). pii: E195. doi: 10.3390/ijerph14020195.
 Shi J, Lin Z, ... Kan H. Cardiovascular Benefits of Wearing Particulate-Filtering Respirators: A Randomized Crossover Trial. Environ Health Perspect. 2017 Feb;125(2):175-180. doi: 10.1289/EHP73. Epub 2016 Aug 26.
 Shi J, Lin Z, ... Kan H. Cardiovascular Benefits of Wearing Particulate-Filtering Respirators: A Randomized Crossover Trial. Environ Health Perspect. 2017 Feb;125(2):175-180. doi: 10.1289/EHP73. Epub 2016 Aug 26.
 Morishita M, Thompson KC, Brook RD. Understanding Air Pollution and Cardiovascular Diseases: Is It Preventable? Curr Cardiovasc Risk Rep. 2015 Jun;9(6). pii: 30.
 Suhaimi MM, Leman AM, ... Gani P. Effectiveness of Indoor Plant to Reduce CO2 in Indoor Environment. MATEC Web of Conferences 103, 2017.
 Homo habilis reconstruction in the Museo de la Evolución Humana, Burgos, sculpture by Elisabeth Daynes (2010) based on the KNM-ER 1813 cranium (Koobi Fora, Kenya, dated 1.9 Ma). CC 4.0 lisence. Source: WikiPedia Homo habilis article. Change made to file name.
 Bloch C. Early Concepts in Investigative Practice— The Case of the Virus. In: Scientific Concepts and Investigative Practice, Feest, U, Steinle F. De Gruyter, 2012, 191-218.
 World Health Organization. WHO Training Package for the Health Sector: Children's Health and the Environment, 2008.
 Leung DYC. Outdoor-indoor air pollution in urban environment: Challenges and opportunity. 2015
 Chen C, Zhao B. Review of relationship between indoor and outdoor particles: I/O ratio, infiltration factor and penetration factor. Atmospheric Environment 45(2) 2011: 275-288.
 Papathanasopoulos P, Preka-Papadema P, ... Kargiotis O. The possible effects of the solar and geomagnetic activity on multiple sclerosis.Clin Neurol Neurosurg. 2016 Jul;146:82-9. doi: 10.1016/j.clineuro.2016.04.023. Epub 2016 Apr 27.
 Alabdulgader A, McCraty R. Long-Term Study of Heart Rate Variability Responses to Changes in the Solar and Geomagnetic Environment. Nature 8 2018.
 Milojević S. Revisiting the connection between Solar eruptions and primary headaches and migraines using Twitter. Sci Rep. 2016 Dec 23;6:39769. doi: 10.1038/srep39769.
 Close J. Are stress responses to geomagnetic storms mediated by the cryptochrome compass system? Proc Biol Sci. 2012 Jun 7;279(1736):2081-90. doi: 10.1098/rspb.2012.0324. Epub 2012 Mar 14.
 Sustainable Development Goal Indicator 3.9.1. WHO.
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Don't expect quick solutions. Building your health is a long-term process - and my blog posts and courses are targeted towards that process.
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